Buscar
Mostrando ítems 1-4 de 4
Post-translational protein arginylation in the normal nervous system and in neurodegeneration
(Wiley Blackwell Publishing, Inc, 2016-08)
Post-translational arginylation of proteins is an important regulator of many physiological pathways in cells. This modification was originally noted in protein degradation during neurodegenerative processes, with an ...
Arginylated Calreticulin Increases Apoptotic Response Induced by Bortezomib in Glioma Cells
(Humana Press, 2019-03)
After retrotranslocation from the endoplasmic reticulum to the cytoplasm, calreticulin is modified by the enzyme arginyltransferase-1 (ATE1). Cellular levels of arginylated calreticulin (R-CRT) are regulated in part by the ...
Ablation of arginyl-tRNA-protein transferase in oligodendrocytes impairs central nervous system myelination
(Wiley-liss, div John Wiley & Sons Inc., 2021-10)
Addition of arginine (Arg) from tRNA can cause major alterations of structure and function of protein substrates. This post-translational modification, termed protein arginylation, is mediated by the enzyme arginyl-tRNA-protein ...
Role of post-translational arginylation in glial cells during CNS myelination
(Wiley, 2019)
Post-translational arginylation of proteins is mediated by Arginyltransferase (Ate1), which modifies multiple substrates, such components of actin cytoskeleton, and modulates biological processes during embryogenesis, cell ...