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Antivirals for COVID-19: A critical review
No specific drugs have been approved for coronavirus disease 2019 (COVID-19) to date as the development of
antivirals usually requires time. Therefore, assessment and use of currently available antiviral drugs is critical ...
Propolis antiviral and immunomodulatory activity: A review and perspectives for COVID-19 treatment
(2021-01-01)
Objectives Viral outbreaks are a frequent concern for humans. A great variety of drugs has been used to treat viral diseases, which are not always safe and effective and may induce adverse effects, indicating the need for ...
Genetic lesions of type i interferon signalling in human antiviral immunity
The concept that type I interferons (IFN-I) are essential to antiviral immunity
derives from studies on animal models and cell lines. Virtually all pathogenic
viruses have evolved countermeasures to IFN-I restriction, ...
Antivirals Against Chikungunya Virus: Is the Solution in Nature?
(Mdpi, 2020-03-01)
The worldwide outbreaks of the chikungunya virus (CHIKV) in the last years demonstrated the need for studies to screen antivirals against CHIKV. The virus was first isolated in Tanzania in 1952 and was responsible for ...