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Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs
(Public Library of Science, 2018-01)
Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in human populations despite widespread herd immunity. Understanding viral mechanisms that enable antigenic evolution is critical for ...
mCSM-AB: a web server for predicting antibody-antigen affinity changes upon mutation with graph-based signatures
(Oxford University Press, 2017)
Malaria transmission structure in the Peruvian Amazon through antibody signatures to Plasmodium vivax
(Public Library of Science, 2022)
Background The landscape of malaria transmission in the Peruvian Amazon is temporally and spatially heterogeneous, presenting different micro-geographies with particular epidemiologies. Most cases are asymptomatic and ...
Heterologous hyperimmune polyclonal antibodies against SARS-COV-2: A broad coverage, affordable, and scalable potential immunotherapy for Covid-19
(2021-09)
The emergence and dissemination of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and the resulting COVID-19 pandemic triggered a global public health crisis.
Although several SARS-CoV-2 vaccines have ...
Variantes de escape del virus de la hepatitis BEscape Mutants of Hepatitis B Virus
(Sociedad Chilena de InfectologíaGrupo de GastrohepatologíaSantiago de Chile, Chile, 2023)
Inhibition of human neutrophil apoptosis by Paracoccidioides brasiliensis: Role of interleukin-8
(2009-02-01)
Paracoccidioidomycosis (PCM) is a systemic mycosis caused by Paracoccidiodes brasiliensis that presents a wide spectrum of clinical manifestations. Because of the great number of neutrophils polymorphonuclear neutrophils ...
Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity
(eLife Sciences, 2020-08)
Although many high-risk mucosal and cutaneous human papillomaviruses (HPVs) theoretically have the potential to synthesize L1 isoforms differing in length, previous seroepidemiological studies only focused on the short L1 ...
Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and corticosteroids
The novel coronavirus, SARS-CoV2, can cause a potentially fatal disease, COVID-19, in humans. Here, we will
provide an overview of therapeutic options for COVID-19. Plasma from patients recovered from COVID-19 that
contains ...
Cetuximab-mediated cellular cytotoxicity is inhibited by HLA-E membrane expression in colon cancer cells
(Sage Publications Ltd, 2009-04)
Cetuximab, an anti-epidermal growth factor receptor monoclonal antibody, has been shown to increase the median survival of colorectal cancer patients. We previously reported that the expression of HLA-E is significantly ...