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Hepatic alteration of tryptophan metabolism in an acute porphyria model. Its relation with gluconeogenic blockage
(Pergamon-Elsevier Science Ltd, 2008-02)
This study focuses on the alterations suffered by the serotoninergic and kinurenergic routes of tryptophan (TRP) metabolism in liver, and their relation with gluconeogenic phosphoenolpyruvate-carboxykinase (PEPCK) blockage ...
Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway
(Soc Experimental Biology Medicine, 2013-02)
A classical acute porphyria model in rats consists of combined treatment with 2-allyl-2-isopropylacetamide (AIA) and 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC). The present work describes the effects of this treatment ...
DAMAGE TO RAT-LIVER MITOCHONDRIA PROMOTED BY DELTA-AMINOLEVULINIC ACID-GENERATED REACTIVE OXYGEN SPECIES - CONNECTIONS WITH ACUTE INTERMITTENT PORPHYRIA AND LEAD-POISONING
(Elsevier Science BvAmsterdamHolanda, 1991)
Effects of volatile anaesthetics on heme metabolism in a murine genetic model of Acute Intermittent Porphyria: A comparative study with other porphyrinogenic drugs
(Elsevier Science, 2018-03)
Background: Acute Intermittent Porphyria (AIP) is an inherited disease produced by a deficiency of Porphobilinogen deaminase (PBG-D). The aim of this work was to evaluate the effects of Isoflurane and Sevoflurane on heme ...
Metabolismo del hemo: las dos caras de los efectos de la acumulación de precursores y porfinasHeme metabolism: the janus nature of precursors and porphyrinsMetabolismo do hemo: as duas faces dos efeitos da acumulação de precursores e porfirinas
(Federación Bioquímica de la Provincia Buenos Aires, 2016-08)
Las Porfirias son enfermedades metabólicas consecuencia de fallas en la biosíntesis del Hemo, caracterizadas por un patrón específico de acumulación y excreción de intermediarios, responsables de su patofisiología. En las ...
Anestésicos volátiles y sus efectos sobre la cadena respiratoria. Regulación de la óxido nítrico sintasa mitocondrialVolatile anaesthetics: Effects on respiratory chain. Regulation of nitric oxide synthase
(2019-03-29)
Las mitocondrias juegan un papel vital en el metabolismo energético; En el interior se produce la fosforilación oxidativa en la cadena de transporte de electrones y la generación de equivalentes de reducción por el ciclo ...