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Nitric oxide alterations in cardiovascular system of rats with Parkinsonism induced by 6-OHDA and submitted to previous exercise
(2018-07-01)
Studies showed that physical exercise decreases the risk of developing Parkinson's disease (PD) as slowing its progression. Nitric oxide (NO) increases in the substantia nigra pars compacta (SNpc) of individuals with PD. ...
Oxidative stress in the medullary respiratory neurons contributes to respiratory dysfunction in the 6-OHDA model of Parkinson's disease
(2020-01-01)
Key points: Parkinson's disease (PD) is associated with respiratory dysfunction. In the 6-OHDA rat model of PD this is seen as a reduction in respiratory frequency and minute ventilation during normoxia and hypercapnia ...
In vitro 6-hydroxydopamine-induced neurotoxicity: New insights on NFκB modulation
(Pergamon-Elsevier Science Ltd, 2019-10)
Neuronal exposure to 6-hydroxydopamine (6-OHDA), a hydroxylated analog of dopamine, constitutes a very useful strategy for studying the molecular events associated with neuronal death in Parkinson's disease. 6-OHDA increases ...
Effects of bilateral ablation or 6-OHDA lesion of the frontal cortex upon the behaviors induced by apomorphine and amphetamine in adult cats
(1998)
The main aim of this study was to compare the effects of bilateral 6- OHDA lesion of the prefrontal, frontal and media cerebral cortex, with those of suction ablation of the same areas, upon apomorphine and amphetamine ...
Efeitos do pré e pós-tratamento com propionato de testosterona nas alterações motoras e neuroquímicas em ratos lesionados por 6-hidroxidopaminaEffects of pre- and post-treatment with testosterone propionate on motor and neurochemical changes in 6- hydroxidopamine rats
(Pós-Graduação em Ciências FisiológicasUniversidade Federal de Sergipe, 2021)
Cardiovascular and autonomic alterations in rats with parkinsonism induced by 6-OHDA and treated with L-DOPA
(2015)
Evaluate the effects caused by L-DOPA on cardiovascular and autonomic parameters in an animal model of Parkinsonism induced by 6-hydroxydopamine (6-OHDA).Adult male Wistar rats were subjected to bilateral microinfusion of ...
Glucose Homeostasis Is Not Affected in a Murine Model of Parkinson's Disease Induced by 6-OHDA
(Frontiers Media Sa, 2019-01-09)
There is a mutual relationship between metabolic and neurodegenerative diseases. However, the causal relationship in this crosstalk is unclear and whether Parkinson's disease (PD) causes a posterior impact on metabolism ...
Cardiovascular evaluation of female rats with 6-OHDA-induced parkinsonism: Possible protection by ovarian hormones and participation of nitric oxide
(Elsevier B.V., 2020-10-15)
Aims: Parkinson's disease (PD) is a neurological disorder caused by environmental and genetic factors, char-acterized by the death of dopaminergic neurons of the substantia nigra pars compacta (SNpc), leading to a decrease ...
Ambiente enriquecido, flexibilidad comportamental y neuroprotección en un modelo animal de parkinson inducido por 6-ohda.
(PsicologíaMaestría en Neuropsicología ClíninicaBogotá, 2020)