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Effects of (−)-6,6′-dinitrohinokinin on adult worms of Schistosoma mansoni: A proteomic analyses
(2016-05-01)
Schistosomiasis, a chronic disease that affects million people worldwide, is caused by trematodeflukes of the genus Schistosoma. The lack of an anti-schistosomiasis vaccine and massive monother-apy with praziquantel ...
In vitro schistosomicidal activity of the lignan ( )-6,60-dinitrohinokinin (dnhk) loaded into poly(lactic-co-glycolic acid) nanoparticles against schistosoma mansoni
(2017-01-01)
Context: ( )-6,60-Dinitrohinokinin (DNHK) display remarkable antiparasitic activity and was, therefore, incorporated into a nanoparticle formulation. Objective: Incorporation of DNHK in poly lactic-co-glycolic acid (PLGA) ...
In vitro and in vivo anthelmintic activity of (-)-6,6 '-dinitrohinokinin against schistosomula and juvenile and adult worms of Schistosoma mansoni
(Elsevier B.V., 2015-09-01)
The chemotherapy of schistosomiasis relies on the use of praziquantel. However, concerns over drug resistance have encouraged the search for new drug leads. This paper is the first report on the in vitro and in vivo activity ...
Evaluación in vitro del efecto del material particulado y un potencial tratamiento en dos líneas celulares
(Universidad Nacional de ColombiaMedellín - Ciencias - Maestría en Ciencias - BiotecnologíaEscuela de biocienciasFacultad de CienciasMedellín, ColombiaUniversidad Nacional de Colombia - Sede Medellín, 2022)
La interacción de los sistemas biológicos con agentes externos puede representar una desregulación de la homeóstasis celular al generar procesos tóxicos, por esto se hace necesario evaluar la exposición a las diferentes ...