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Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA (“Ecstasy”) in Rats and Preserves Affinity for the Serotonin Transporter (SERT)
(Frontiers Media S.A., 2019)
The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. ...
Behavioral Profiles in Rats Distinguish Among "Ecstasy," Methamphetamine and 2,5-Dimethoxy-4-Iodoamphetamine: Mixed Effects for "Ecstasy" Analogues
(AMER PSYCHOLOGICAL ASSOC, 2010-06-30)
3,4-methylenedioxymethamphetamine (MDMA; “ecstasy”) is a psychoactive drug structurally related to
other phenylisopropylamines acting as stimulants or hallucinogens in humans. Although MDMA has a
pharmacological identity ...
The Variability Of Ecstasy Tablets Composition In Brazil
(WILEY-BLACKWELLHOBOKEN, 2015)
3,4-Methylenedioxymethamphetamine (Ecstasy) Decreases Inflammation and Airway Reactivity in a Murine Model of Asthma
(KARGERBASEL, 2012)
Objective:3,4-Methylenedioxymethamphetamine(MDMA), or ecstasy, is a synthetic drug used recreationally, mainly by young people. It has been suggested that MDMA has a Th cell skewing effect, in which Th1 cell activity is ...
Forensic electrochemistry: Simultaneous voltammetric detection of MDMA and its fatal counterpart dr Death (PMA)
(2016-01-07)
The simultaneous detection of substances present in drugs of abuse is increasingly important since some materials are known for their high mortality rate. One drug that received considerable attention is para-methoxyamphetamine ...
Differential behavioral outcomes of 3,4-methylenedioxymethamphetamine (MDMA-ecstasy) in anxiety-like responses in mice
(Associação Brasileira de Divulgação Científica, 2011)
Anxiolytic and anxiogenic-like behavioral outcomes have been reported for methylenedioxymethamphetamine (MDMA or ecstasy) in rodents. In the present experiment, we attempted to identify behavioral, hormonal and neurochemical ...
Disposition of MDMA and Metabolites in Human Sweat Following Controlled MDMA Administration
(AMER ASSOC CLINICAL CHEMISTRY, 2009)
BACKGROUND: Understanding the excretion of 3,4-methylenedioxymethamphetamine (MDMA) and metabolites in sweat is vital for interpretation of sweat tests in drug treatment, criminal justice, and workplace programs. METHODS: ...
A Window into the Intoxicated Mind? : speech as an Index of Psychoactive Drug Effects
(Nature Publishing Group, 2014-04)
Abused drugs can profoundly alter mental states in ways that may motivate drug use. These effects are usually assessed with self-report, an approach that is vulnerable to biases. Analyzing speech during intoxication may ...