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P2O5/SiO2 : A Simple and Effective Catalyst for the Synthesis of N-substituted 1-Alkyl and 1-Aryl 3-Aminoisoquinolines
(Bentham Science Publishers, 2013-04)
A synthesis of N-substituted 1-alkyl and 1-aryl 3-aminoisoquinolines by cyclocondensation of 2- acylphenylacetonitriles with aliphatic and aromatic amines using P2O5/SiO2 as catalysts is described. Selectivity, simplicity ...
Microwave-induced Synthesis of N-Substituted 1-Alkyl and 1-Aryl 3-Aminoisoquinolines
(Bentham Science Publishers, 2017-03)
Background: Aminoisoquinolines are an important class of heterocyclic compounds. These compounds present a wide range of pharmacological properties including antimalaric, anticonvulsant and anti-inflammatory. Although ...