P2O5/SiO2 : A Simple and Effective Catalyst for the Synthesis of N-substituted 1-Alkyl and 1-Aryl 3-Aminoisoquinolines

Mendez, Leticia Jesica; Cánepa, Alicia Susana; Rimada, Rubén; Bravo, Rodolfo Daniel

Artículos de revistas

Fecha

2013-04

Registro en:

Mendez, Leticia Jesica; Cánepa, Alicia Susana; Rimada, Rubén; Bravo, Rodolfo Daniel; P2O5/SiO2 : A Simple and Effective Catalyst for the Synthesis of N-substituted 1-Alkyl and 1-Aryl 3-Aminoisoquinolines; Bentham Science Publishers; Letters In Organic Chemistry; 10; 4; 4-2013; 240-244

1570-1786

http://hdl.handle.net/11336/23147

CONICET Digital

CONICET

http://repositorioslatinoamericanos.uchile.cl/handle/2250/1876296

Autor

Mendez, Leticia Jesica

Cánepa, Alicia Susana

Rimada, Rubén

Bravo, Rodolfo Daniel

Institución

Consejo Nacional de Investigaciones Científicas y Tecnológicas (Argentina)

Resumen

A synthesis of N-substituted 1-alkyl and 1-aryl 3-aminoisoquinolines by cyclocondensation of 2- acylphenylacetonitriles with aliphatic and aromatic amines using P2O5/SiO2 as catalysts is described. Selectivity, simplicity of operation and easy work-up are some advantages of this method.

Materias

P2O5/SiO2

3-AMINOISOQUINOLINES

2-ACYLPHENYLACETONITRILES

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