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Wound-healing and benzodiazepines: does sleep play a role in this relationship?
(Faculdade de Medicina / USP, 2012-07-01)
Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines ...
ELECTROCHEMICAL CHARACTERIZATION OF NEW 1,5-BENZODIAZEPINE DERIVATIVES
(Sociedad Chilena de Química, 2014-07)
Cyclic voltammetry was used to study the electrochemical behavior of new 1,5-benzodiazepine derivatives on a glassy carbon electrode. Well-defined oxidation peaks were observed in DMSO. The Electrochemical response of the ...
Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions
(2009)
1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave ...
Boron-Doped Diamond Electrode Coupled to Liquid Chromatography: Application to Simultaneous Determination of Benzodiazepines
(Wiley-v C H Verlag GmbhWeinheimAlemanha, 2010)
4-(2-Hydroxyphenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine and the 2-(2,3-dimethoxyphenyl)-, 2-(3,4-dimethoxyphenyl)- and 2-(2,5-dimethoxyphenyl)-substituted derivatives
(BLACKWELL PUBLISHING, 2007-07)
The 1,5-benzodiazepine ring system exhibits a puckered boatlike conformation for all four title compounds [4-(2-hydroxyphenyl)2- phenyl-2,3-dihydro-1H-1,5-benzodiazepine, C21H18N2O, (I), 2-(2,3-dimethoxyphenyl)-4-(2-hydr ...
Involvement of GABA(A)-benzodiazepine receptor in the anxiolytic effect induced by hexanic fraction of Rubus brasiliensis
(Elsevier B.V., 1998-06-01)
To investigate the ability of hexanic ethanolic fraction of Rubus brasiliensis Martius (Roseceae), to induce anxiolytic effect and also the possible involvement of the GABA(A)-benzodiazepine receptor complex, male Wistar ...
Plano de intervenção do uso e abuso de benzodiazepínicos na Unidade de Saúde Zona D na cidade de Paula Cândido Minas Gerais
(Universidade Federal de Minas GeraisUFMG, 2014-04-12)
The benzodiazepines use and abuse is a public health problem, being observed inappropriate use in several countries. Benzodiazepines depressant drugs are central nervous system classified as sedative-hypnotics, and cause ...
Benzodiazepine use in Chile: Impact of availability on use, abuse, and dependence
(1996)
This study tested the hypothesis whether over-the-counter benzodiazepine availability influenced patterns of benzodiazepine use, abuse, and dependence in Chile. If over-the-counter availability represents a major risk ...