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Neutrophils suppress γδ T-cell function
(Wiley VCH Verlag, 2013-12)
γδ T cells have been shown to stimulate the recruitment and activation of neutrophils through the release of a range of cytokines and chemokines. Here, we investigated the reverse relationship, showing that human neutrophils ...
γδ T lymphocytes: An effector cell in autoimmunity and infection
(Frontiers Media SA, 2018-10)
γδ T cells are non-conventional lymphocytes which show several properties of innate immune cells. They present a limited TCR repertoire and circulate as cells with a pre-activated phenotype thus being able to generate rapid ...
CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cells
(2009)
γδ T cells are a potent source of innate IL-17A and IFN-γ, and they acquire the capacity to produce these cytokines within the thymus. However, the precise stages and required signals that guide this differentiation are ...
CD3 expression distinguishes two γδT cell receptor subsets with different phenotype and effector function in tuberculous pleurisy
(Wiley Blackwell Publishing, Inc, 2009-09)
Summary Tuberculous pleurisy is a naturally occurring site of Mycobacterium tuberculosis (Mtb) infection. Herein, we describe the expression of activation, natural killer (NK) and cell migration markers, as well as effector ...
Mucosal and systemic γδ+ T cells associated with control of simian immunodeficiency virus infection
(American Association of Immunologists, 2016)
Gamma delta T cells act as a first line of defense against invading pathogens. However, despite their abundance in mucosal tissue, little information is available about their functionality in this compartment in the context ...
γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis
(Nature America Inc, 2022)
Modulation of γδ T-cell activation by neutrophil elastase
(Wiley Blackwell Publishing, Inc, 2017-09)
γδ T cells are non-conventional, innate-like T cells, characterized by a restricted T-cell receptor repertoire. They participate in protective immunity responses against extracellular and intracellular pathogens, tumour ...
Glioblastoma cells potentiate the induction of the Th1-like profile in phosphoantigen-stimulated γδ T lymphocytes
(Springer, 2021-06)
Purpose: γδ T lymphocytes are non-conventional T cells that participate in protective immunity and tumor surveillance. In healthy humans, the main subset of circulating γδ T cells express the TCRVγ9Vδ2. This subset responds ...
Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
(2023-01-03)
γδ T cells are involved in the control of Staphylococcus aureus infection, but their importance in protection compared to other T cells is unclear. We used a mouse model of systemic S. aureus infection associated with high ...