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Improvement of galangin solubility using native and derivative cyclodextrins. An UV-Vis and NMR study
(2009)
The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydroxypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ...
Binding of Sulfamethazine to β-cyclodextrin and Methyl-β-cyclodextrin
(Springer, 2013-04)
β-cyclodextrin (βCD) and methyl-β-cyclodextrin (MβCD) complexes with sulfamethazine (SMT) were prepared and characterized by different experimental techniques, and the effects of βCD and MβCD on drug solubility were assessed ...
Influence of β-Cyclodextrin Methylation on Host-Guest Complex Stability: A Theoretical Study of Intra- and Intermolecular Interactions as Well as Host Dimer Formation
(2023)
Understanding the non-covalent interactions in host-guest complexes is crucial to their stability, design and applications. Here, we use density functional theory to compare the ability of β-cyclodextrin (β-CD) and ...
Complexation between darunavir ethanolate and beta cyclodextrin: experimental and theoretical studies
(2014)
Darunavir (DRV) is a protease inhibitor used in the treatment of HIV infection, which constitutes a keystone in the therapy of patients infected with this virus. Unfortunately, DRV has low solubility in water and poor ...
β-Cyclodextrin grafted gold nanoparticles with short molecular spacers applied for nanosensors based on plasmonic effects
(Elsevier Science, 2019-06)
The detection and quantification of organic molecules is of vital importance in many areas as Biochemistry, Medicine, Environmental Chemistry, etc. The Supramolecular systems as macrocycles form host guest complexes that ...
First solid-state NMR spectroscopy evaluation of complexes of benznidazole with cyclodextrin derivatives
(Elsevier, 2015-10)
Complexation of benznidazole (BZL), a drug of choice for the treatment of Chagas'neglected disease, with cyclodextrin (CD) derivatives was analyzed by solid-state NMR. 13C cross polarization/magic angle spinning spectra ...
Complexation of herbicide bentazon with native and modified β-cyclodextrin
(2010)
For first time the complexation of bentazon (Btz) with native β-cyclodextrin (β-CD) and modified sulfobutylether-β-CD (SBE-CD) was studied by differential pulse voltammetry. In addition, a spectrophotometry UV-Visible study ...
Inclusion Complexes of Cyclodextrins with Galangin: a Thermodynamic and Reactivity Study
(SPRINGER/PLENUM PUBLISHERS, 2010-10)
The formation of the complexes of galangin (GAL) with native β-cyclodextrin
(βCD), and with its substituted counterparts such as dimethyl-βCD (DMβCD) and
hydroxypropyl-βCD (HPβCD), was studied by fluorescence spectra in ...
Ternary complexation of benzoic acid with β-cyclodextrin and aminoacids. Experimental and theoretical studies
(Springer, 2016-06)
β-Cyclodextrin (β-CD) is a well-known host molecule used to prepare inclusion complexes. Considering that the three dimensional array of these complexes depends on the inclusion mode of the guest molecule within the β-CD ...