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Alzheimer disease: 100 years later
(Sociedad Médica de Santiago, 2001)
Modulating amyloid fibrillation in a minimalist model peptide by intermolecular disulfide chemical reduction
(Royal Society of Chemistry, 2019-05)
Peptide structural transformation and aggregation is associated with a large number of outsider aetiology diseases, and it is intrinsically linked to amyloid peptide aggregation. Diphenylalanine self-assembled structures ...
Amyloid-ß-peptide reduces copper(II) to copper(I) independent of its aggregation state
(Sociedad de Biología de Chile, 2000)
Apoptosis is directly related to intracellular amyloid accumulation in a cell line derived from the cerebral cortex of a trisomy 16 mouse, an animal model of Down syndrome
(ELSEVIER, 2010)
Human Down syndrome (DS) represents the most frequent cause of mental retardation associated to
a genetic condition. DS also exhibits a characteristic early onset of neuropathology indistinguishable
from that observed ...
Caracterização de modelos de experimentação baseados na Doença de Alzheimer em zebrafish
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2015)
New animal models for neurodegenerative diseases study are necessary for the knowledge of molecular mechanisms and behavioral patterns involved on the progression of dementias as Alzheimer’s Disease (AD) as well as for new ...
Caracterização de modelos de experimentação baseados na Doença de Alzheimer em zebrafish
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2015)
New animal models for neurodegenerative diseases study are necessary for the knowledge of molecular mechanisms and behavioral patterns involved on the progression of dementias as Alzheimer’s Disease (AD) as well as for new ...
Avaliação do efeito do adoçante artificial aspartame, sobre moscas Drosophila melanogaster, modelo da cascata ß-amilóideEvaluation of the effect of artificial sweetener aspartame on Drosophila melanogaster flies, model of the ß-amyloid cascade
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Genética e Bioquímica, 2021)
El 17β-estradiol disminuye la expresión y asociación de quinasas responsables de la hiperfosforilación de Tau
(2012-11-30)
Introducción: Un componente molecular predominante en el estudio de las enfermedades neurodegenerativas es la
presencia del complejo Tau-GSK3β y su asociación con agregados proteicos al interior de la célula. Evidencias ...