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Supraorganized collagen enhances Schwann cell reactivity and organization in vitro
(Associação Brasileira de Divulgação Científica, 2011)
Diabetes reduces mesenchymal stem cells in fracture healing through a TNF alpha-mediated mechanism
(Springer, 2015-03-01)
Diabetes interferes with bone formation and impairs fracture healing, an important complication in humans and animal models. The aim of this study was to examine the impact of diabetes on mesenchymal stem cells (MSCs) ...
Effects of combined nicotine and fluoxetine treatment on adult hippocampal neurogenesis and conditioned place preference
(Elsevier, 2015-08)
Adult neurogenesis occurs in mammals within the dentate gyrus, a hippocampal subarea. It is known to be induced by antidepressant treatment and reduced in response to nicotine administration. We checked here whether the ...
Chronic stress decreases the expression of sympathetic markers in the pineal gland and increases plasma melatonin concentration in rats
(BLACKWELL PUBLISHING, 2006-06)
Chronic stress affects brain areas involved in learning and emotional responses. Although most studies have concentrated on the effect of stress on limbic-related brain structures, in this study we investigated whether ...
Conduto de orientação nervosa funcionalizado com células estromais mesenquimais multipotentes promove a regeneração do nervo isquiático em ratos
(Universidade Estadual Paulista (Unesp), 2020-10-19)
As lesões traumáticas do sistema nervoso periférico (SNP) são altamente debilitantes, levando a déficits sensório-motores a longo prazo. A regeneração nervosa depende de um microambiente permissivo para o crescimento axonal, ...
Protective effects of the neurosteroid allopregnanolone in a mouse model of spontaneous motoneuron degeneration
(Pergamon-Elsevier Science Ltd., 2017-11)
Amyotrophic lateral sclerosis (ALS) is a devastating disorder characterized by progressive death of motoneurons. The Wobbler (WR) mouse is a preclinical model sharing neuropathological similarities with human ALS. We have ...
3D-printed nerve guidance conduits multi-functionalized with canine multipotent mesenchymal stromal cells promote neuroregeneration after sciatic nerve injury in rats
(2021-12-01)
Background: Nerve injuries are debilitating, leading to long-term motor deficits. Remyelination and axonal growth are supported and enhanced by growth factor and cytokines. Combination of nerve guidance conduits (NGCs) ...
Efecto del ambiente enriquecido posterior a la separación materna, sobre el bdnf y los astrocitos en la corteza cerebral de ratas wistar
(Universidad Nacional de ColombiaBogotá - Medicina - Maestría en FisiologíaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2022-10-28)
Las interacciones madre-hijo influyen en la fisiología, desarrollo y el comportamiento durante las primeras semanas después del nacimiento. Como una experiencia adversa en la vida temprana, la separación materna (SM), ...