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On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions
(Elsevier B.V., 2012-06-01)
Five 2-hydroxy-3-substituted-aminomethyl naphthoquinones, nine 1,2,3-triazolic para-naphthoquinones, five nor-beta-lapachone-based 1,2,3-triazoles, and several other naphthoquinonoid compounds were synthesized and evaluated ...
Breast Cancer Targeting of a Drug Delivery System through Postsynthetic Modification of Curcumin@N3-bio-MOF-100 via Click Chemistry
(2021-08-16)
Metal-organic frameworks (MOFs) offer many opportunities for applications across biology and medicine. Their wide range of chemical composition makes toxicologically acceptable formulation possible, and their high level ...
Clickable-Zwitterionic Copolymer Capped-Quantum Dots for in Vivo Fluorescence Tumor Imaging
(American Chemical Society, 2018-04)
In the last decades, fluorescent quantum dots (QDs) have appeared as high-performance biological fluorescent nanoprobes and have been explored for a variety of biomedical optical imaging applications. However, many central ...
Reversible polymerization of novel monomers bearing furan and plant oil moieties: a double click exploitation of renewable resources
(ROYAL SOC CHEMISTRYCAMBRIDGE, 2012)
Monomers based on plant oil derivatives bearing furan heterocycles appended through thiol-ene click chemistry were prepared and, subsequently, polymerized via a second type of click reaction, i. e. the Diels-Alder (DA) ...
Modificação química da superfície de nanocristais de celulose via reação click para a obtenção de bionanomateriais funcionais
(Universidade Federal de Minas GeraisUFMG, 2015-07-29)
In this work we aimed at the preparation of surface functionalized cellulose nanocrystals (NCC) with two bioactive molecules with potential anticancer activity (alkyne-1,4-naftoquinone QA, and azide-1,4-naftoquinone QN3) ...
SÍNTESE E AVALIAÇÃO DAS ATIVIDADES FUNGICIDA, FITOTÓXICA E CITOTÓXICA DE NOVOS 1,2,3-TRIAZÓIS A PARTIR DO GLICEROL
(Universidade Federal do Espírito SantoBRPrograma de Pós-Graduação em AgroquímicaUFESMestrado em Agroquímica, 2019-02-18)
O uso de produtos químicos na agricultura é uma das estratégias de manejo que apresenta a melhor relação custo benefício. Entretanto, esses compostos estão sujeitos a uma série de problemas de resistência de microrganismo ...
Bio-sourced networks from thermal polyaddition of a starch-derived α-Azide-ω-Alkyne AB monomer with an A2B2 aliphatic cross-linker
(American Chemical Society, 2010-06-02)
A starch-derived α-azide-ω-alkyne 1,4:3,6-dianhydrohexitol AB monomer and a novel symmetrical heterofunctional A2B2 aliphatic cross-linker, i.e., 2,2-bis(azidomethyl)-1,3-bis(O-propargyl) propanediol, were copolymerized ...
Chemoenzymatic resolution of β-azidophenylethanols by candida antarctica and their application for the synthesis of chiral benzotriazoles
(Sociedade Brasileira de Química, 2013-09-01)
The kinetic resolutions of (±)-β-azidophenylethanols were carried out using lipase from Candida antarctica, and enantiomerically enriched (R)-β-azidophenylethanols and their corresponding (S)-β-azidophenylethyl acetates ...