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Role of Heme Oxygenase-1 in Polymyxin B-Induced Nephrotoxicity in Rats
(AMER SOC MICROBIOLOGYWASHINGTON, 2012)
Polymyxin B (PMB) is a cationic polypeptide antibiotic with activity against multidrug-resistant Gram-negative bacteria. PMB-induced nephrotoxicity consists of direct toxicity to the renal tubules and the release of reactive ...
Efficacy of Endodontic Treatment for Endotoxin Reduction in Primarily Infected Root Canals and Evaluation of Cytotoxic Effects
(Elsevier B.V., 2012-08-01)
Introduction: Endotoxins are one of the etiologic agents involved in the pathogenesis of apical periodontitis. The objectives of this clinical study were to investigate the effects of endodontic treatment by using different ...
Efficacy of Endodontic Treatment for Endotoxin Reduction in Primarily Infected Root Canals and Evaluation of Cytotoxic Effects
(Elsevier B.V., 2012-08-01)
Introduction: Endotoxins are one of the etiologic agents involved in the pathogenesis of apical periodontitis. The objectives of this clinical study were to investigate the effects of endodontic treatment by using different ...
In vitro evaluation of the action of irrigating solutions associated with intracanal medications on Escherichia coli and its endotoxin in root canals
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2011-03-01)
Objective: The purpose of this study was to evaluate the efficacy of auxiliary chemical substances and intracanal medications on Escherichia coli and its endotoxin in root canals. Material and Methods: Teeth were contaminated ...
Design of mucoadhesive gellan gum and chitosan nanoparticles intended for colon-specific delivery of peptide drugs
(2021-11-05)
Nanotechnology has been widely used in the development of polymer nanocarriers for the oral delivery of biomolecules. The use of nanostructured systems can improve drug delivery and help to overcome the disadvantages of ...
A novel pH-responsive hydrogel-based on calcium alginate engineered by the previous formation of polyelectrolyte complexes (PECs) intended to vaginal administration
(2017-10-03)
This work aimed to develop a calcium alginate hydrogel as a pH responsive delivery system for polymyxin B (PMX) sustained-release through the vaginal route. Two samples of sodium alginate from different suppliers were ...
Atividade antibacteriana de nitrato de gálio frente à isolados de Klebsiella pneumoniae resistentes à polimixina BAntibacterial activity of galium nitrate against polymixin b resistant Klebsiella pneumoniae isolates
(Universidade Federal da Grande DouradosBrasilFaculdade de Ciências Biológicas e AmbientaisUFGD, 2022)
In vitro evaluation of the action of irrigating solutions associated with intracanal medications on Escherichia coli and its endotoxin in root canals
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2014)
Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz, 2019)