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Expressão e atividade da enzima conversora da angiotensina I como biomarcador de hipertensão, Na urina de receptores de transplante renal pediátricos
(Universidade Federal de São Paulo (UNIFESP), 2018-03-29)
Pediatric hypertension is a risk factor for hypertension in adults with prevalence
between 1 and 5%. Its hereditary component is estimated at 50 %. Primary hypertension results
from genetic, environmental, and behavioral ...
Modulation of the action of insulin by angiotensin-(1-7)
(Portland Press, 2014-05)
The prevalence of Type 2 diabetes mellitus is predicted to increase dramatically over the coming years and the clinical implications and healthcare costs from this disease are overwhelming. In many cases, this pathological ...
Eje Renina Angiotensina, Enzima Convertidora de Angiotensina 2 y Coronavirus
(Sociedad Chilena de Pediatría, 2020)
El sistema renina angiotensina aldosterona (SRAA) es el principal regulador del volumen plasmático,
manteniendo la homeostasis cardiovascular e hidrosalina. En la vía clásica, la enzima convertidora de
angiotensina (ECA) ...
Renin-angiotensin-aldosterone system and COVID-19 infection
With the multiplication of COVID-19 severe acute respiratory syndrome cases due to SARS-COV2, some
concerns about angiotensin-converting enzyme 1 (ACE1) inhibitors (ACEi) and angiotensin II type 1
receptor blockers (ARB) ...
Efeitos da hiperprolactinemia experimental sobre a histomorfometria e a expressão gênica do receptor de prolactina no endométrio de camundongas e sua interação com esteróides sexuais
(Universidade Federal de São Paulo (UNIFESP), 2009-04-26)
Specific ACE2 expression in small intestinal enterocytes may cause gastrointestinal symptoms and injury after 2019-nCoV infection
The coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China and rapidly spread in other
countries in December 2019. The infected patients presented with fever, respiratory symptoms,
sometimes with digestive ...
Clinical impact of an angiotensin I-converting enzyme insertion/deletion and kinin B2 receptor +9/-9 polymorphisms in the prognosis of renal transplantation
(Walter de Gruyter & Co, 2013-03-01)
There is a consensus in the scientific literature that supports the importance of the kallikrein kinin and renin angiotensin systems in renal physiology, but few studies have investigated their importance after renal ...
Hypotheses about sub-optimal hydration in the weeks before coronavirus dis‐ ease (COVID-19) as a risk factor for dying from COVID-19
To address urgent need for strategies to limit mortality from coronavirus disease 2019 (COVID-19), this review describes experimental, clinical and epidemiological evidence that suggests that chronic sub-optimal hydration ...
Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif
(American Society for Biochemistry and Molecular Biology, 2021-09)
The spike protein is the main protein component of the SARS-CoV-2 virion surface. The spike receptor-binding motif mediates recognition of the human angiotensin-converting enzyme 2 (hACE2) receptor, a critical step in ...