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Perspectives and Challenges in the Fight Against COVID-19: The Role of Genetic Variability
(2021-03-15)
In the last year, the advent of the COVID-19 pandemic brought a new consideration for the multidisciplinary sciences. The unknown mechanisms of infection used by SARS-CoV-2 and the absence of effective antiviral pharmacological ...
Ethanol intake-induced apoptosis in glial cells and axonal disorders in the cerebellar white matter of UChA rats (voluntary ethanol consumers)
(Elsevier B. V., 2015)
Ethanol intake may cause alterations in cellular metabolism altering motricity, learning and cognition. The cerebellum is one of the most susceptible organs to ethanol-related disorders during development, and is associated ...
Efecto de la rosiglitazona sobre la respuesta celular inflamatoria en la cicatrización de pacientes con diabetes mellitus tipo 2
(Universidad Michoacana de San Nicolás de Hidalgo, 2007-03)
Type 2 Diabetes Mellitus (DM2) is conditioned by multiple pathophysiological mechanisms, associated with environmental and genetic factors, causing insulin resistance and β-cell dysfunction of the pancreas, healing is ...
Bradykinin inducible receptor is essential to lipopolysaccharide-induced acute lung injury in mice
(ELSEVIER SCIENCE BV, 2010)
Lipopolysaccharides from gram-negative bacteria are amongst the most common causative agents of acute lung injury, which is characterized by an inflammatory response, with cellular infiltration and the release of ...
Fotobiomodulação em células de pele humana envolvidas no processo de reparo tecidual
(Universidade Federal de Santa MariaBrasilCiências da SaúdeUFSMPrograma de Pós-Graduação em Reabilitação FuncionalCentro de Ciências da Saúde, 2020-09-18)
Treatment with an LED photobiomodulation is a widely used resource without tissue repair
with promising results. However, in cancer physiotherapy, it is more in the prevention of
radiodermatitis, the use of the resource ...
Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells
(PERGAMON-ELSEVIER SCIENCE LTD, 2004-05)
Chronic ethanol consumption leads to cell injury in virtually every tissue. Tumor necrosis factor-alpha (TNF-alpha) constitutes a major factor in the development of alcohol-induced liver injury. In alcohol-dependent subjects, ...
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
(NATL ACAD SCIENCES, 2018)
Abnormal modifications to mutant superoxide dismutase 1 (SOD1) are linked to familial amyotrophic lateral sclerosis (fALS). Misfolding of wild-type SOD1 (SOD1(WT)) is also observed in postmortem tissue of a subset of ...
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
(National Academy of Sciences, 2018)
Abnormal modifications to mutant superoxide dismutase 1 (SOD1) are linked to familial amyotrophic lateral sclerosis (fALS). Misfolding of wild-type SOD1 (SOD1(WT)) is also observed in postmortem tissue of a subset of ...
Efeitos da suplementação com melatonina sobre a hipertrofia e a hiperplasia de adipócitos isolados do tecido adiposo subcutâneo de camundongos obesos
(Universidade Federal de São Paulo, 2018-06)
Atualmente, a obesidade tornou-se um problema de saúde pública de proporções epidêmicas, além disso a obesidade é considerada fator de risco para o desenvolvimento de diabetes mellitus tipo 2, hipertensão, doença coronariana, ...