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Direct Spinal Ventral Root Repair Following Avulsion: Effectiveness Of A New Heterologous Fibrin Sealant On Motoneuron Survival And Regeneration
(Hindawi Publishing CorpNew York, 2016)
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling.
(2015)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which pathogenesis and death of motor neurons are triggered by non-cell-autonomous mechanisms. We showed earlier that exposing primary rat spinal ...
Progesterone treatment of spinal cord injury: effects on receptors, neurotrophins and myelination
(Humana Press, 2006-01)
In addition to its traditional role in reproduction, progesterone (PROG) has demonstrated neuroprotective and promyelinating effects in lesions of the peripheral and central nervous systems, including the spinal cord. The ...
The delective glucocorticoid receptor modulator cort 113176 reduces neurodegeneration and neuroinflammation in Wobbler mice spinal cord
(Pergamon-Elsevier Science Ltd, 2018-08)
Wobbler mice are experimental models for amyotrophic lateral sclerosis. As such they show motoneuron degeneration, motor deficits, and astrogliosis and microgliosis of the spinal cord. Additionally, Wobbler mice show ...
Comparative effects of progesterone and the synthetic progestin norethindrone on neuroprotection in a model of spontaneous motoneuron degeneration
(Pergamon-Elsevier Science Ltd, 2019-09)
The Wobbler mouse has been proposed as an experimental model of the sporadic form of amyotrophic lateral sclerosis (ALS). The administration of natural progesterone (PROG) to Wobbler mice attenuates neuropathology, inhibits ...
Models of passive and active dendrite motoneuron pools and their differences in muscle force control
(SPRINGERDORDRECHT, 2012)
Motoneuron (MN) dendrites may be changed from a passive to an active state by increasing the levels of spinal cord neuromodulators, which activate persistent inward currents (PICs). These exert a powerful influence on MN ...