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Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells
(WILEY-LISS, 2008)
The effect of unbound palmitic acid (PA) at plasma physiological concentration range on reactive oxygen species (ROS) production by cultured rat skeletal muscle cells was investigated. The participation of the main sites ...
Isotropic exchange interaction between Mo and the proximal FeS center in the xanthine oxidase family member aldehyde oxidoreductase from Desulfovibrio gigas on native and polyalcohol inhibited samples: an EPR and QM/MM study
(Springer, 2014-10)
Aldehyde oxidoreductase from Desulfovibrio gigas (DgAOR) is a homodimeric molybdenum-containing protein that catalyzes the hydroxylation of aldehydes to carboxylic acids and contains a Mo-pyranopterin active site and two ...
2-acetylphenothiazine protects L929 fibroblasts against UVB-induced oxidative damage
(2021-03-01)
Ultraviolet B (UVB) light corresponds to 5% of ultraviolet radiation. It is more genotoxic and mutagenic than UVA and causes direct and indirect cellular damage through the generation of reactive oxygen species (ROS). Even ...
Global Reach 2018: Nitric oxide-mediated cutaneous vasodilation is reduced in chronic, but not acute, hypoxia independently of enzymatic superoxide formation
(Elsevier, 2021)
We tested the hypotheses that 1) cutaneous microvascular function is impaired by acute normobaric and chronic hypobaric hypoxia and 2) that the superoxide free radical (via NADPH oxidase or xanthine oxidase) contributes ...
Determinación del potencial inhibitorio de la fracción alcaloidal de Psychotria stenostachya sobre xantina oxidasa y radical superóxido mediante autografía.
(Escuela Superior Politécnica de Chimborazo, 2020-02-18)
The main objective of this investigation was to determine the inhibitory potential of the alkaloidal fraction of Psychotria stenostachya on xanthine oxidase and superoxide radical by autography. In the first instance, an ...
Determinación del potencial inhibitorio de la fracción alcaloidal de Palicourea amethystina sobre xantinoxidasa y radical superóxido mediante autografía.
(Escuela Superior Politécnica de Chimborazo, 2019-12-03)
The objective of the investigation was to determine the inhibitory activity of xanthine oxidase (XO) and superoxide radical (RSO) by the alkaloid extract of Palicourea amethystina (belonging to the Rubiaceae family) by ...
Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters
(ELSEVIER SCIENCE INC, 2011)
BACKGROUND: Increased oxidative stress in heart failure (HF) leads to inflammation and endothelial dysfunction (ED). Both statins and allopurinol have known anti-oxidant properties, but their utility in HF has not been ...
BIOLOGICALLY ACTIVE COMPOUNDS FROM CHILEAN PROPOLIS
(Sociedad Chilena de Química, 2000)
Loss of the metal binding properties of metallothionein induced by hydrogen peroxide and free radicals
(1997)
The relationship between the metal-binding properties of metallothionein (MT) and its ability to interact with peroxides and free radicals was explored in vitro. The binding of 109Cd to MT and the thiol density of the ...
Flavonoid-enriched fractions from Parastrephia lucida: Phytochemical, anti-inflammatory, antioxidant characterizations, and analysis of their toxicity
(Elsevier Science, 2020-12)
Parastrephia lucida (Meyen) Cabrera is an endemic species from the Argentinean Puna used in traditional medicine to relieve inflammation. To give scientific support to the ethnopharmacological claim, a bio-guided fractionation ...