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Memantine agonist action at dopamine D2High receptors
(Veterinary and Human Toxicology, 2008-02)
Memantine is reported to improve symptoms in moderate cases of Alzheimer´s disease and Parkinson´s disease, but is also known to trigger psychosis in some Parkinson patients. Because these clinical features suggested a ...
Active and Total Transforming Growth Factor-{beta}1 are Differentially Regulated by Dopamine and Estradiol in the Pituitary
(Endocrine Society, 2011-07)
Dopamine, acting through the dopamine type 2 receptor (Drd2), is the main inhibitor of pituitary prolactin (PRL) secretion and lactotroph proliferation. TGF-β1 is involved, at least in part, in mediating these actions. It ...
Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson’s disease
(Taylor and Francis Ltd, 2017)
Dopamine D1 and Glutamate N-Methyl-D-Aspartate Receptors: An Essential Interplay in Prefrontal Cortex Synaptic Plasticity
(Springer, 2007)
The aim of the present chapter is to provide a brief overview on DA (mostly via D1 receptors) contribution to synaptic plasticity in the prefrontal cortex and consider new insights into the possible cellular mechanisms ...
Two-Photon Optical Interrogation of Individual Dendritic Spines with Caged Dopamine
(American Chemical Society, 2013-05)
We introduce a novel caged dopamine compound (RuBi-Dopa) based on ruthenium photochemistry. RuBi-Dopa has a high uncaging efficiency and can be released with visible (blue-green) and IR light in a two-photon regime. We ...
Distinctive modulation of dopamine release in the nucleus accumbens shell mediated by dopamine and acetylcholine receptors
(Society for Neuroscience, 2017-11-15)
Nucleus accumbens (NAc) shell shows unique dopamine (DA) signals in vivo and plays a unique role in DA-dependent behaviors such as reward-motivated learning and the response to drugs of abuse.Adisynaptic mechanism forDArelease ...
Genes Differentially Expressed in Prolactinomas Responsive and Resistant to Dopamine Agonists
(KARGER, 2009)
Background/Aims: Prolactin (PRL) secretion and its gene expression are inhibited by dopamine. Prolactinomas are the most common secreting pituitary adenomas, and dopamine agonists (DA) are the first choice for their ...