Buscar
Mostrando ítems 61-70 de 1257
The impact of the suppression of highly connected protein interactions on the corona virus infection
(Nature, 2022)
Several highly effective Covid-19 vaccines are in emergency use, although more-infectious coronavirus strains, could delay the end of the pandemic even further. Because of this, it is highly desirable to develop fast ...
Interaction network and localization of Brucella abortus membrane proteins involved in the synthesis, transport, and succinylation of cyclic β-1,2-glucans
(American Society for Microbiology, 2015-03)
Cyclic β-1,2-glucans (CβG) are periplasmic homopolysaccharides that play an important role in the virulence and interaction of Brucella with the host. Once synthesized in the cytoplasm by the CβG synthase (Cgs), CβG are ...
Lysozyme adsorption in pH-responsive hydrogel thin-films: the non-trivial role of acid-base equilibrium
(Royal Society of Chemistry, 2015-07)
We develop and apply a molecular theory to study the adsorption of lysozyme on weak polyacid hydrogel films. The theory explicitly accounts for the conformation of the network, the structure of the proteins, the size and ...
Protein complex prediction via dense subgraphs and false positive analysis
(Public Library Science, 2017)
Many proteins work together with others in groups called complexes in order to achieve a
specific function. Discovering protein complexes is important for understanding biological
processes and predict protein functions ...
An Integrative Genomic and Transcriptomic Analysis Reveals Potential Targets Associated with Cell Proliferation in Uterine Leiomyomas
(2013-03-04)
Background: Uterine Leiomyomas (ULs) are the most common benign tumours affecting women of reproductive age. ULs represent a major problem in public health, as they are the main indication for hysterectomy. Approximately ...
An Integrative Genomic and Transcriptomic Analysis Reveals Potential Targets Associated with Cell Proliferation in Uterine Leiomyomas
(2013-03-04)
Background: Uterine Leiomyomas (ULs) are the most common benign tumours affecting women of reproductive age. ULs represent a major problem in public health, as they are the main indication for hysterectomy. Approximately ...
Convergent evolution and mimicry of protein linear motifs in host-pathogen interactions
(Elsevier Science London, 2015-06)
Pathogen linear motif mimics are highly evolvable elements that facilitate rewiring of host protein interaction networks. Host linear motifs and pathogen mimics differ in sequence, leading to thermodynamic and structural ...
Discriminating Different Classes of Biological Networks by Analyzing the Graphs Spectra Distribution
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2012)
The brain's structural and functional systems, protein-protein interaction, and gene networks are examples of biological systems that share some features of complex networks, such as highly connected nodes, modularity, and ...