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Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors
(Public Library Of Science, 2014-04)
Platelets contribute to vessel formation through the release of angiogenesis-modulating factors stored in their α-granules. Galectins, a family of lectins that bind β-galactoside residues, are up-regulated in inflammatory ...
Platelet-mediated angiogenesis is independent of VEGF and fully inhibited by aspirin
(Wiley Blackwell Publishing, Inc, 2013-09)
Background and Purpose Platelets are major players in every step of vessel development through the local delivery of angiogenesis-modulating factors, including the pro-angiogenic protein VEGF and the anti-angiogenic ...
Estudo da modulação das células mielóides supressoras no adenocarcinoma metastático após terapia antiangiogênica
(Universidade Federal de São Paulo (UNIFESP), 2016-08-31)
Renal cell carcinoma (RCC), the third leading cause of death in genitourinary cancers. RCCs are highly vascularized and resistant to radiotherapy and chemotherapy. Antiangiogenic drugs are promising and widely used in ...
Novel pathogenic mutations and skin biopsy analysis in Knobloch syndrome
(MOLECULAR VISION, 2009)
Purpose: To facilitate future diagnosis of Knobloch syndrome (KS) and better understand its etiology, we sought to identify not yet described COL18A1 mutations in KS patients. In addition, we tested whether mutations in ...