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Regulation of the Norepinephrine Transporter by Endothelins: A potential therapeutic target
(Elsevier Academic Press Inc, 2015-03)
Neuronal norepinephrine (NE) uptake is a crucial step in noradrenergic neurotransmission that regulates NE concentration in the synaptic cleft. It is a key mechanism mediated by the NE transporter (NET) which takes the ...
Endothelin-Mediated Calcium Responses in Supraoptic Nucleus Astrocytes Influence Magnocellular Neurosecretory Firing Activity
(Wiley Blackwell Publishing, Inc, 2012-02)
In addition to their peripheral vasoactive effects, accumulating evidence supports an important role for endothelins (ETs) in the regulation of the hypothalamic magnocellular neurosecretory system, which produces and ...
Endothelin isoforms and the response to myocardial stretch
(American Physiological Society, 2005-12)
Myocardial stretch elicits a biphasic increase in developed force with a first rapid force response and a second slow force response (SFR). The rapid phase is due to an increase in myofilament Ca(2+) responsiveness; the ...
Stretch-Elicited Autocrine/Paracrine Mechanism in the Heart
(Springer, 2003)
Endotelina-1: vasoconstrictor intrínseco del endotelio vascular
(Universidad Militar Nueva Granada, 2013)
Role of IL-18 in overt pain-like behaviour in mice
(ELSEVIER SCIENCE BV, 2008)
There are evidences that targeting IL-18 might be beneficial to inhibit inflammatory symptoms, including hypernociception (decrease in nociceptive threshold). The mechanism of IL-18 mechanical hypernociception depends on ...