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Frizzled-1 receptor regulates adult hippocampal neurogenesis
(2016)
Abstract
Background
In the adult hippocampus new neurons are continuously generated from neural stem cells (NSCs) present at the subgranular zone of the dentate gyrus. This ...
Expression Profile of Rat Hippocampal Neurons Treated with the Neuroprotective Compound 2,4-Dinitrophenol: Up-Regulation of cAMP Signaling Genes
(SPRINGER, 2010)
2,4-Dinitrophenol (DNP) is classically known as a mitochondrial uncoupler and, at high concentrations, is toxic to a variety of cells. However, it has recently been shown that, at subtoxic concentrations, DNP protects ...
Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons.
(Wiley, 2014)
Serotonin (5-HT) production and expression of 5-HT receptors (5-HTRs) occur early during prenatal development. Recent evidence suggests that, in addition to its classical role as a neurotransmitter, 5-HT regulates neuronal ...
Heparin activates Wnt signaling for neuronal morphogenesis
(WILEY, 2008)
Writ factors are secreted ligands that affect different aspects of the nervous system behavior like neurodevelopment, synaptogenesis and neurodegeneration. In different model systems, Wnt signaling has been demonstrated ...
SRPKs regulate aggregation of ELKS2 and modulates synaptogenesis in dissociated hippocampal neurons
(2016)
ELKS2 is an active zone protein (AZ) that forms
macromolecular complexes with other proteins of the
cytomatrix of the AZ through the interaction with Munc-13,
RIM1, Piccolo and Bassoon. Due to this multiple interactions
ELKS2 ...
Astaxanthin protects primary hippocampal neurons against noxious effects of A β-oligomers
(Hindawi Limited, 2016)
© 2016 Pedro Lobos et al.Increased reactive oxygen species (ROS) generation and the ensuing oxidative stress contribute to Alzheimer's disease pathology. We reported previously that amyloid-β peptide oligomers (AβOs) produce ...
Antioxidant and neuroprotective effects of mGlu3 receptor activation on astrocytes aged in vitro
(Pergamon-Elsevier Science Ltd, 2020-11)
Astrocytes play a key role by providing antioxidant support to nearby neurons under oxidative stress. We have previously demonstrated that in vitro astroglial subtype 3 metabotropic glutamate receptor (mGlu3R) is ...