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Molecular Characterization of Extended-Spectrum beta-Lactamase-Producer Klebsiella pneumoniae Isolates Causing Neonatal Sepsis in Peru
(American Society of Tropical Medicine and Hygiene, 2016)
Klebsiella pneumoniae (KP) is the most common cause of neonatal sepsis in the low- and middle-income countries. Our objective was to describe the phenotypic and molecular characteristics of extended-spectrum beta-lactamase ...
Antibotic resistance in Zn(II)-deficient environments: activation of metallo-beta-lactamases in the periplasm
(Future Medicine, 2013-07)
Zn(II) is an essential metal ion in living organisms, playing a wide variety of roles as a structural, regulatory or catalytic cofactor in proteins. As is the case for most transition metal ions, high Zn(II) levels are ...
The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop
(American Society for Microbiology, 2018-12)
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria. Unfortunately, the worldwide spread of ...
Cefepime versus extended spectrum β-lactamase-producing Enterobacteriaceae
(Brazilian Society of Infectious Diseases, 2011-04-01)
The objective of this study was to evaluate the susceptibility to cefepime of a large group of ESBL- producing enterobacteria recently isolated in a Brazilian teaching hospital . The study included 280 strains of ESBL-producing ...
Resistencia de la bacteria Escherichiacoli por la beta-lactamasas.// Resistence of the bacterium Escherichia coli by beta-lactamases
(Universidad Estatal de Milagro, 2017)