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Mostrando ítems 51-60 de 249
Antisense S-oligodeoxynucleotides down-regulate TGF?-production by kupffer cells from CCl4-injured rat livers
(1997)
TGF? is a pleiotropic cytokine involved in multiple physiological and pathophysiological regulatory mechanisms. Since TGF? is a disparate modulator of cell recruitment, proliferation and extracellular matrix phenotype for ...
In vivo knockdown of antisense non-coding mitochondrial RNAs by a lentiviral-encoded shRNA inhibits melanoma tumor growth and lung colonization
(Wiley, 2018)
The family of non-coding mitochondrial RNAs (ncmtRNA) is differentially expressed according to proliferative status. Normal proliferating cells express sense (SncmtRNA) and antisense ncmtRNAs (ASncmtRNAs), whereas tumor ...
Adrenalectomy promotes a permanent decrease of plasma corticoid levels and a transient increase of apoptosis and the expression of Transforming Growth Factor β1 (TGF-β1) in hippocampus: Effect of a TGF-β1 oligo-antisense
(2006)
Background: Corticosterone reduction produced by adrenalectomy (ADX) induces apoptosis in dentate gyrus (DG) of the hippocampus, an effect related to an increase in the expression of the pro-apoptotic gene bax. However it ...
A Cytoplasmic New Catalytic Subunit of Calcineurin in Trypanosoma cruzi and Its Molecular and Functional Characterization
(Public Library Science, 2014-01-01)
Parasitological cure for Chagas disease is considered extremely difficult to achieve because of the lack of effective chemotherapeutic agents against Trypanosoma cruzi at different stages of infection. There are currently ...
Reduced Ampk2 Protein Expression Restores Glucose-induced Insulin Secretion In Islets From Calorie-restricted Rats
(Wiley-BlackwellHoboken, 2016)
Ventricular Myosin Light Chain-2 Gene Expression in Developing Heart of Chicken Embryos
(Sociedad de Biología de Chile, 2001)
Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus
(1996)
Among the numerous endocrine signals that affect the central nervous system, sex steroids play an important role. It has been recently postulated that part of the effects of these hormones on the brain may be mediated by ...
Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus
(1996)
Among the numerous endocrine signals that affect the central nervous system, sex steroids play an important role. It has been recently postulated that part of the effects of these hormones on the brain may be mediated by ...
Apical distribution of HFE-β2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells
(2006)
Mutations in the HFE gene result in hereditary hemochromatosis, a disorder of iron metabolism characterized by increased intestinal iron absorption. Based on the observation that ectopic expression of HFE strongly inhibits ...