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Estudo da ação dicotômica do receptor de estrógeno beta (ERβ) na indução da transição epitélio- mesênquima em células tumorais de mama da linhagem MCF-7Study of dicotomic action of beta estrogen receptor (ERΒ) in breast cancer: role in cell proliferation and epithelium- mesenchymal transition (EMT) in luminal breast cancer cell line MCF-7
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Imunologia e Parasitologia Aplicadas, 2018)
Influência da terapêutica hormonal estrogênica e do treinamento de força sobre o tecido muscular esquelético de ratas senis
(Universidade Estadual Paulista (Unesp), 2016-08-22)
A diminuição das concentrações plasmáticas de estrógeno está intimamente relacionada com o aumento do estresse oxidativo e a diminuição da massa muscular em idosos. A terapêutica hormonal estrogênica (THE) e o treinamento ...
Receptores estrogênicos regulam a expressão e a função de β-catenina e Galectina-3 em células de câncer de próstata independentes de androgênios DU-145
(Universidade Federal de São Paulo, 2022-05-12)
O câncer prostático inicialmente responde bem à terapia de ablação androgênica, mas em muitos casos o tumor progride para um fenótipo independente de androgênios ou também denominado resistente à castração (CRPC, castration ...
Estrous cycle disruptor effect of an ethanolic extract from Buddleja globosa leaves and its main component (verbascoside) Efecto disruptor del ciclo estral de un extracto etanólico de hojas de Buddleja globosa y de su componente principal (verbascósido)
(Universidad de Santiago de Chile, 2014)
The estrous cycle disruptor effect of an ethanolic extract (EMATst) from Buddleja globosa leaves and standardized in its main component (verbascoside) was determined in rats after the subcutaneous administration of EMATst. ...
Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta
(2019-04-15)
Palmitic acid (PA) induces several metabolic and molecular changes in astrocytes, and, it is involved in pathological conditions related to neurodegenerative diseases. Previously, we demonstrated that tibolone, a synthetic ...
Steroid hormones and estrogenic activity in the wastewater outfall and receiving waters of the Chascomús chained shallow lakes system (Argentina)
(Elsevier, 2020-11-15)
Natural and synthetic steroid hormones, excreted by humans and farmed animals, have been considered as important sources of environmental endocrine disruptors. A suite of estrogens, androgens and progestogens was measured ...
Bisphenol A disrupts the temporal pattern of histofunctional changes in the female reproductive tract of Caiman latirostris
(Academic Press Inc Elsevier Science, 2017-12)
Recently, we have described the ontogeny of histofunctional differentiation changes in the oviduct of Caiman latirostris. The expression of estrogen receptor alpha and progesterone receptor shows that the caiman oviduct ...
Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats
(Elsevier Ireland, 2015-02)
We investigated whether neonatal exposure to low doses of endosulfan affects fertility and uterine functional differentiation at pre-implantation in rats. Newborn female rats received the vehicle, 0.2 μg/kg/d of ...
Paxillin, a novel controller in the signaling of estrogen to FAK/N-WASP/Arp2/3 complex in breast cancer cells
(Elsevier Ireland, 2016-07-15)
Breast cancer is the major cause of cancer-related death in women. Its treatment is particularly difficult when metastasis occurs. The ability of cancer cells to move and invade the surrounding environment is the basis of ...