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Effectiveness of treatment of high-grade multiple cutaneous mast cell tumour using tyrosine kinase inhibitor and vinblastine: case reportEfectividad del tratamiento de mastocitoma cutáneo múltiple de alto grado usando un inhibidor de tirosina quinasa y vinblastina: reporte de caso
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria, 2021)
Current Patient Management of Chronic Myeloid Leukemia in Latin America A Study by the Latin American Leukemia Net (LALNET)
(JOHN WILEY & SONS INCEstados Unidos, 2010)
Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats
(Springer-verlagNew YorkEUA, 2003)
Nilotinib is associated with a reduced incidence of BCR-ABL mutations vs imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase
(Amer Soc HematologyWashingtonEUA, 2013)
Resistance acquired to third generation tyrosine kinase inhibitors in non small cell lung cancerResistencia adquirida a inhibidores de tirosina kinasa de tercera generación en cáncer de pulmón de células no pequeñas
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2018)
Avaliação do uso de inibidores de tirosina quinase em pacientes com leucemia mielóide crônica
(Universidade Federal de Santa MariaBrasilAnálises Clínicas e ToxicológicasUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2016-08-26)
Chronic myeloid leukemia (CML) results from the clonal proliferation of a hematopoietic stem cell representing approximately 15-20% of all cases of leukemia. It is characterized by the presence of the Philadelphia chromosome ...
C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same.
(2023)
Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as “c-Abl”). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an ...