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Conformational Properties of Angiotensin II and Its Active and Inactive TOAC-Labeled Analogs in the Presence of Micelles. Electron Paramagnetic Resonance, Fluorescence, and Circular Dichroism Studies
(Wiley-Blackwell, 2009-01-01)
The interaction between angiotensin II (AII, DRVYIHPF) and its analogs carrying 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid (TOAC) and detergents-negatively charged sodium dodecyl sulfate (SDS) and ...
Structural features that make oligopeptides susceptible substrates for hydrolysis by recombinant thimet oligopeptidase
(Portland Press, 1997-06-01)
A systematic analysis of the peptide sequences and lengths of several homologues of bioactive peptides and of a number of quenched-fluorescence (qf) opioid- and bradykinin-related peptides was performed to determine the ...
Dissecting the mechanism of action of actinoporins. Role of the N-terminal amphipathic alpha-helix in membrane binding and pore activity of sticholysins I and II
(Public Library Science, 2018-08-30)
Actinoporins sticholysin I and sticholysin II (St I, St II) are proposed to lyse model and biomembranes via toroidal pore formation by their N-terminal domain. Based on the hypothesis that peptide fragments can reproduce ...
Specificity of the dynorphin-processing endoprotease: Comparison with prohormone convertases
(Lippincott Williams & Wilkins, 1999-05-01)
The cleavage specificity of a monobasic processing dynorphin converting endoprotease is examined with a series of quench fluorescent peptide substrates and compared with the cleavage specificity of prohormone convertases, ...
Development of an operational synaptobrevin-based fluorescent substrate for tetanus neurotoxin quantification
(Portland Press, 2002-12-01)
Tetanus neurotoxin (TTx), produced by Clostridium tetani, is a two-chain polypeptide with a heavy molecular chain (HC; 100 kDa) and a light molecular chain (LC; 50 kDa) linked by a disulphide bridge. the low-molecular-mass ...
Preparação e caracterização de nanocápsulas peptídicas destinadas à veiculação de compostos terapêuticos
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Bioquimica e Fisiologia, 2018)