Buscar
Mostrando ítems 41-50 de 1039
Impact of population admixture on the distribution of immune response co-stimulatory genes polymorphisms in a Brazilian population
(Elsevier B.V., 2015-11-01)
Co-stimulatory molecules are essential in the orchestration of immune response and polymorphisms in their genes are associated with various diseases. However, in the case of variable allele frequencies among continental ...
IL28B polymorphisms are markers of therapy response and are influenced by genetic ancestry in chronic hepatitis C patients from an admixed population
(WILEY-BLACKWELLHOBOKEN, 2012)
Background: IL28B polymorphisms are predictors of therapy response in hepatitis C virus (HCV) patients. We do not know whether they are markers of treatment response in admixed populations or not. Aims: To determine whether ...
IL28B polymorphisms are markers of therapy response and are influenced by genetic ancestry in chronic hepatitis C patients from an admixed population
(2012)
Background IL28B polymorphisms are predictors of therapy response in hepatitis C virus (HCV) patients. We do not know whether they are markers of treatment response in admixed populations or not.
Aims To determine whether ...
Variation in dental morphology and inference of continental ancestry in admixed Latin Americans
(Wiley-Liss Inc., 2019)
© 2018 Wiley Periodicals, Inc. Objectives: To investigate the variation in dental nonmetric traits and to evaluate the utility of this variation for inferring genetic ancestry proportions in a sample of admixed Latin ...
A global reference for human genetic variation
(Springer Nature, 2015)
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report ...
Locus-specific ancestry to detect recent response to selection in admixed Swiss Fleckvieh cattle
(2016-12-01)
Identification of selection signatures is one of the current endeavors of evolutionary genetics. Admixed populations may be used to infer post-admixture selection. We calculated local ancestry for Swiss Fleckvieh, a composite ...
Extended HLA-G genetic diversity and ancestry composition in a Brazilian admixed population sample: Implications for HLA-G transcriptional control and for case-control association studies
(2018-11-01)
Human leukocyte antigen-G (HLA-G) is a nonclassical Major Histocompatibility Complex (MHC) molecule with immunomodulatory function and restricted tissue expression. The genetic diversity of HLA-G has been extensively studied ...