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Understanding the structural mechanism of selective blockers of pH-gated K2P channels
(2018)
Two-‐pore
domain
potassium
(K2P)
channels
underlie
the
background
K+
currents
in
mammalian
cells.
They
can
be
segregated
into
six
subfamilies
based
on
their
structure
and
functional
properties.
The
acid-‐
sensitive
TAS ...
Study and discovery of TASK potassium channels modulators: A theoretical and experimental approach
(2016)
Two-pore domain potassium (K2P) channels underlie the background K+ currents in mammalian cells; these can be segregated into six subfamilies based on their structure and functional properties. The acid-sensitive TASK-1 ...
A new prominent TASK-3 activator: a molecular study
(2017)
The two-pore domain potassium (K2P) channels contribute to the background leak potassium currents in
nearly all cells regulating the resting membrane potential. K2P channels represent important clinical targets for
the ...