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Antarctic environments as a source of bacterial and fungal therapeutic enzymes
(2022-01-01)
Microbial therapeutic enzymes are the protagonists in the pharmacological treatment of different human diseases. The intrinsic enzymatic characteristics, such as high affinity and specificity to the corresponding substrate, ...
Biological markers for evaluating therapeutic efficacy in Chagas disease, a systematic review
(Taylor & Francis, 2014-03)
The most neglected aspects of Chagas disease (CD) have been patient care and treatment. Despite recent progress in the development of potentially improved drugs, there is no consensus among different research groups on the ...
Eficacia de los azoles en el tratamiento de la leishmaniasis cutáneaEfficacy of azoles in the treatment of cutaneous leishmaniasis
(Internet Medical PublishingSalud y SostenibilidadPrograma de Estudio y Control de Enfermedades Tropicales (PECET)Oviedo, España, 2021)
Relative bioavailability and comparative clinical efficacy of different ivermectin oral formulations in lambs
(Biomed Central, 2013-02-11)
Several oral ivermectin (IVM) formulations for use in sheep are available in the pharmaceutical veterinary market in different countries. All of them are indicated at the same dose rate to treat the gastrointestinal ...
Therapeutic effects of Salmonella Typhi in a mouse model of T-cell lymphoma
(Lippincott Williams, 2013-04)
In this study, we assessed the effectiveness of a live, attenuated Salmonella enterica serovar Typhi (S. Typhi) vaccine strain as a cancer immunotherapy in a mouse model of metastatic T-cell lymphoma. EL4 tumor-bearing ...
Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy?
Several recent pharmacogenetic studies have investigated the variability in both outcome and toxicity in cisplatin-based therapies. These studies have focused on the genetic variability of therapeutic targets that could ...
Antihistaminergics and inverse agonism. Potential therapeutic applications
(Elsevier, 2013-09)
The accurate characterization of the molecular mechanisms involved in the action of receptor ligands is important for their appropriate therapeutic use and safety. It is well established that ligands acting at the histamine ...
Therapeutic efficacy of florfenicol against Streptoccoccus agalactiae infection in nile tilápia (Oreochromis nicoticus)
(Universidade Federal de Minas GeraisUFMG, 2016-01-29)
Streptococcus agalactiae is one of the most important pathogens affecting farm-raised tilapia worldwide. The oral therapy with antibiotics is the main therapeutic measure applied in outbreaks. Several antimicrobial agents ...