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A prion-like domain of Tpk2 catalytic subunit of protein kinase A modulates P-body formation in response to stress in budding yeast
(Elsevier Science, 2021-01)
Low complexity regions are involved in the assembly and disassembly of P-bodies (PBs). Saccharomyces cerevisiae contains three genes encoding the protein kinase A (PKA) catalytic subunit: TPK1, TPK2 and TPK3. Tpk2 and Tpk3 ...
Structure of yeast regulatory subunit: a glimpse into the evolution of PKA signaling
(Elsevier, 2010-11)
The major cAMP receptors in eukaryotes are the regulatory (R) subunits of PKA, an allosteric enzyme conserved in fungi through mammals. While mammals have four R-subunit genes, Saccharomyces cerevisiae has only one, Bcy1. ...
The gap gene giant of Rhodnius prolixus is maternally expressed and required for proper head and abdomen formation
(Academic Press Inc Elsevier Science, 2012-01)
The segmentation process in insects depends on a hierarchical cascade of gene activity. The first effectors downstream of the maternal activation are the gap genes, which divide the embryo in broad fields. We discovered a ...
Sterol regulatory element-binding protein (Sre1) promotes the synthesis of carotenoids and sterols in xanthophyllomyces dendrorhous
(Frontiers Media S.A., 2019)
Xanthophyllomyces dendrorhous is a basidiomycete yeast that synthesizes carotenoids, mainly astaxanthin, which are of great commercial interest. Currently, there are many unknown aspects related to regulatory mechanisms ...
RasGEF1b: localização celular de seus domínios e papel regulador negativo sobre a ativação de NF-kappaB
(Universidade Federal de Minas GeraisUFMG, 2011-07-29)
The guanine nucleotide exchange factor RasGEF1b is a protein encoded by a gene whose expression is strongly induced in response to stimuli with Toll-like receptor (TLR) agonists. RasGEF1b is found localized at the early ...
Nuclear matrix protein Matrin 3 regulates alterna tive splicing and forms overlapping regulatory networks with PTB
(Nature Publishing Group, 2015-01)
Matrin3 is an RNA‐ and DNA‐binding nuclear matrix protein found to be associated with neural and muscular degenerative diseases. A number of possible functions of Matrin3 have been suggested, but no widespread role in RNA ...
ADP-glucose Pyrophosphorylase; a Regulatory Enzyme for Bacterial Glycogen Synthesis
(American Society for Microbiology, 2003-12)
ADP-Glucose Pyrophosphorylase, a Regulatory Enzyme forBacterial Glycogen SynthesisMiguel A. Ballicora,1 Alberto A. Iglesias,2 and Jack Preiss1*Department of Biochemistry and Molecular Biology, Michigan State University, ...
The carboxy terminal domain of RNA polymerase II and alternative splicing
(Cell Press, 2010-09)
Alternative splicing is controlled by cis-regulatory sequences present in the pre-mRNA and their cognate trans-acting factors, as well as by its coupling to RNA polymerase II (pol II) transcription. A unique feature of ...
A regulatory RNA is involved in RNA duplex formation and biofilm regulation in sulfolobus acidocaldarius
(Oxford University Press, 2018-05-18)
Non-coding RNAs (ncRNA) are involved in essential biological processes in all three domains of life. The regulatory potential of ncRNAs in Archaea is, however, not fully explored. In this study, RNA-seq analyses identified ...
Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)