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In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii
(SOC BRASILEIRA MEDICINA TROPICALBRASILIA, 2012)
Introduction: Toxoplasmosis is usually a benign infection, except in the event of ocular, central nervous system (CNS), or congenital disease and particularly when the patient is immunocompromised. Treatment consists of ...
Efficacy of a diarylheptanoid derivative against Leishmania amazonensis
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Leishmanicidal Activities of Novel Synthetic Furoxan and Benzofuroxan Derivatives
(Amer Soc Microbiology, 2014-08-01)
A novel series of furoxan (1,2,5-oxadiazole 2-oxide) (compounds 3, 4a and -b, 13a and -b, and 14a to -f) and benzofuroxan (benzo[c][1,2,5] oxadiazole 1-oxide) (compounds 7 and 8a to -c) derivatives were synthesized, ...
Phenotypic diversity and drug susceptibility of Trypanosoma cruzi TcV clinical isolates
(PLoS, 2018)
Trypanosoma cruzi is a genetically heterogeneous group of organisms that cause Chagas disease. It has been long suspected that the clinical outcome of the disease and response to therapeutic agents are, at least in part, ...
Phenotypic diversity and drug susceptibility of Trypanosoma cruzi TcV clinical isolates
(Public Library of Science, 2018-09)
Trypanosoma cruzi is a genetically heterogeneous group of organisms that cause Chagas disease. It has been long suspected that the clinical outcome of the disease and response to therapeutic agents are, at least in part, ...
Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis
(Journal of Ethnopharmacology, 1992)
The stem barks of Pera benensis are employed by the Chimane Indians in the Bolivian Amazonia as treatment of cutaneous leishmaniasis caused by the protozoan Leishmania braziliensis. The chloroform extracts containing ...
Synthesis and in vitro activity of limonene derivatives against Leishmania and Trypanosoma
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2010)
The synthesis and in vitro activity of R(+)-Limonene derivatives against Leishmania and Trypanosoma cruzi strains are reported. Seven compounds have shown better in vitro activity against Leishmania (V.)braziliensis than ...
Nanotechnological strategies for treatment of leishmaniasis-a review
(2017-02-01)
The World Health Organization (WHO) estimates that more than one billion people suffer from neglected tropical diseases. Leishmaniasis is a widespread disease, affecting 12 million people around the world with about 1-2 ...