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Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
(Acad Sciences Czech Republic, Inst Physiology, 2005-01-01)
In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, ...
Interferon-Beta e IL-12 sinergizam para a produção de interferon-gama em células mononucleares humanas
(Sociedade Brasileira de Medicina Tropical, 2020)
P2X(7) receptor activation amplifies lipopolysaccharide-induced vascular hyporeactivity via interleukin-1 beta release
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2008)
Lipopolysaccharide (LPS) stimulates cytoplasmic accumulation of pro-interleukin (IL)-1 beta. Activation of P2X(7) receptors stimulates conversion of pro-IL-1 beta into mature IL-1 beta, which is then secreted. Because both ...
Interleukin-4 and interleukin-13 inhibit the expression of leukemia inhibitory factor and interleukin-11 in fibroblasts
(Pergamon-Elsevier B.V. Ltd, 2012-01-01)
Cytokines produced by inflammatory or resident mesenchymal cells play important modulatory roles in the pathogenesis of inflammation induced bone loss. In the present study, the effects of IL-4 and IL-13 on the expression ...
α-MSH and γ-MSH modulate early release of hypothalamic PGE2 and NO induced by IL-1β differently
(Elsevier Ireland, 2006-12)
Interleukin-1beta (IL-1beta) stimulates corticotropin-releasing hormone (CRH) secretion in hypothalamus, which involves the release of prostaglandins (PGE2) and nitric oxide (NO). We have demonstrated that melanocortins ...
Immunomodulatory effect of cathelicidins in response to a beta-glucan in intestinal epithelial cells from rainbow trout
(Elsevier, 2015)
The aim of the present study was to characterize intestinal immune mechanisms involved in the response to beta-glucans in rainbow trout. Among the immune effectors regulated in response to immunostimulants, host defense ...
MTA-induced neutrophil recruitment: a mechanism dependent on IL-1 beta, MIP-2, and LTB(4)
(MOSBY-ELSEVIER, 2008)
Objective. The objective of this study was to investigate the mediators and the resident peritoneal cells involved in the neutrophil migration (NM) induced by mineral trioxide aggregate (MTA) in mice. Study design. MTA (25 ...
Terpinen-4-ol and alpha-terpineol (tea tree oil components) inhibit the production of IL-1 beta, IL-6 and IL-10 on human macrophages
(Springer, 2014-09-01)
Tea tree oil (TTO) is an essential oil with anti-inflammatory properties, steam distilled from the plant Melaleuca alternifolia. We investigated the immunomodulatory properties of TTO and its components (terpinen-4-ol and ...