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Conserved high activity binding peptides are involved in adhesion of two detergent-resistant membrane-associated merozoite proteins to red blood cells during invasion
Detergent resistant membranes (DRMs) of Plasmodium falciparum merozoites contain a large number of glycosylphosphatidylinositol (GPI)-anchored proteins that have been implicated in interactions between merozoites and red ...
The Cryptosporidium parvum gp60 glycoprotein expressed in the ciliate Tetrahymena thermophila is immunoreactive with sera of calves infected with Cryptosporidium oocysts
(Elsevier Science, 2019-07)
Cryptosporidium parvum is a protozoan parasite of the phylum Apicomplexa responsible for cryptosporidiosis in calves, a disease that causes significant diarrhea and impairs gain of body weight, generating important production ...
Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)
Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ...
Identification of novel vaccine candidates against cryptosporidiosis of neonatal bovines by reverse vaccinology
(Elsevier, 2018-12)
The apicomplexan protozoan Cryptosporidium parvum is an important causative agent of diarrhea of neonatal bovines. Vaccination has been proposed as an advantageous strategy against cryptosporidiosis of calves since besides ...
Genetic Structure and Expression of the Surface Glycoprotein GP82, the Main Adhesin of Trypanosoma cruzi Metacyclic Trypomastigotes
(Hindawi Publishing Corporation, 2013-01-01)
T. cruzi improves the likelihood of invading or adapting to the host through its capacity to present a large repertoire of surface molecules. the metacyclic stage-specific surface glycoprotein GP82 has been implicated in ...
High polymorphism in Plasmodium vivax merozoite surface protein-5 (MSP5)
A key issue relating to developing multi-component anti-malarial vaccines, lies in studying Plasmodium vivax surface proteins' genetic variation. The present work was aimed at amplifying, cloning and sequencing the gene ...
Glicosilfosfatidilinositol como alvo terapêutico e vacinal contra doenças parasitárias intracelularesGlycosylphosphatidylinositol as a therapeutic and vaccine target against intracellular parasitic diseases
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Imunologia e Parasitologia Aplicadas, 2021)