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Synthesis of the C7-C24 fragment of (-)-Macrolactin F
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
An enantioselective and convergent synthesis of the C7-C24 fragment of Macrolactin F was achieved from four main fragments. A hydrotelluration/transmetalation sequence was used to install the E,Z diene present in the ...
An improved stereospecific synthesis of (Z,E)-9, 11, 13-Tetradecatrienal. Sex pheromone component of Stenoma cecropia
(2000)
(Z,E)-9,11,13-tetradecatrienal, a pheromone component of Stenoma cecropia, was prepared in 61% overall yield from 1-nonyne. The synthesis involved two palladium-catalyzed cros-couplings to afford a 1,3-dien5-yne, which was ...
Estudio de síntesis de quinonas heterocíclicas derivadas de benzofuranoquinonas: obtención de derivados de rhinacantona. aplicación de nuevos parámetros en relaciones estructura-actividad
(2005)
El objetivo general de la presente tesis fue la síntesis de quinonas heterocíclicas derivadas de benzofuranoquinonas con actividad biológica potencial.
Este estudio se inicia con la síntesis de una serie de derivados ...
Síntesis y evaluación biológica in vivo de un nuevo análogo del androstano con actividad potencial sobre la biosíntesis y acción de andrógenos endógenos
(2014)
Con la finalidad de contribuir al descubrimiento y desarrollo de moléculas novedosas para el tratamiento de desórdenes androgénicos de alta incidencia en la población masculina, como el cáncer de próstata e hiperplasia ...
Biomimetic Nitration of Conjugated Linoleic Acid: Formation and Characterization of Naturally Occurring Conjugated Nitrodienes
(American Chemical Society, 2014-01)
Nitro-conjugated linoleic acids (NO2-cLA), endogenous nitrodiene lipids which act as inflammatory signaling mediators, were isolated and single isomers purified from the biomimetic acidic nitration products of conjugated ...
Alteration of the Route to Menaquinone towards Isochorismate-Derived Metabolites
(Wiley VCH Verlag, 2019-07)
Chorismate and isochorismate constitute branch-point intermediates in the biosynthesis of many aromatic metabolites in microorganisms and plants. To obtain unnatural compounds, we modified the route to menaquinone in ...
A convenient synthesis of benzo[g]pyrrolo[3,2-c]quinoline-6,11-diones
(2005)
The synthesis of a new class of angular tetracyclic quinones is described. Our strategy involves Diels-Alder reaction of pyrroloquinolinequinone 9, generated in situ from pyrroloquinoline 8, and dienes. The required ...