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Preparación de derivados 1,2,3-triazol-lapachol vía click chemistry
(Universidad de Talca (Chile). Escuela de Tecnología Médica., 2018)
Modified ribavirin analogues as antiviral agents against Junín virus
(Elsevier, 2019-02)
In this work, several ribavirin analogues were synthesized and incorporated into a multivalent arrangement. Both were subsequently modified by the addition of polyhydroxylated residues. Their antiviral activity was tested ...
Chemoenzymatic Synthesis of Triazololactams Structurally Related to Pancratistatin
(Wiley VCH Verlag, 2017-07-17)
Four tricyclic lactams that structurally resemble alkaloids with the pancratistatin skeleton were synthetized from bromobenzene by a chemoenzymatic strategy. The sequence involved enzymatic dihydroxylation, efficient ...
Kinetics of the epoxy-thiol click reaction initiated by a tertiary amine: Calorimetric study using monofunctional components
(Elsevier Science, 2015-08-08)
An analysis of the kinetics of the epoxy–thiol reaction in a model stoichiometric system of monofunctional reagents, 3-mercaptopropionate (BMP) and phenylglycidylether (PGE) is reported. Benzyldimethylamine (BDMA) was ...
Multicomponent synthesis of 1,2,3-triazoles in water catalyzed by copper nanoparticles on activated carbon
(Wiley VCH Verlag, 2010-12)
Copper nanoparticles on activated carbon have been found to effectively catalyze the multicomponent synthesis of 1,2,3-triazoles from different azide precursors, such as organic halides, diazonium salts, anilines and ...
Síntese de novos derivados triazólicos e avaliação de suas atividades antifúngicas
(Universidade Federal de Minas GeraisBrasilPrograma de Pós-Graduação em QuímicaUFMG, 2019-08-20)
In the last three decades, the mortality rate caused by fungal infections has substantially increased due the appearance of new pathogenic fungi and the emergence of infections resistant to the available drugs for treatment. ...
Antimicrobial Activity of Amphiphilic Triazole-Linked Polymers Derived from Renewable Sources
(2016-03-14)
Conventional engineered polymers are strong, stable, and can interact desirably within the human body in implants and medical devices. However, bacterial colonization of medical devices and implants constructed from these ...
Dimeric Labdane Diterpenes: Synthesis and Antiproliferative Effects
(MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, 2013)