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Decreased production of TNF-alpha by lymph node cells indicates experimental autoimmune encephalomyelitis remission in Lewis rats
(Instituto Oswaldo Cruz, Ministério da Saúde, 2010-05-01)
Experimental autoimmune encephalomyelitis (EAE) is mediated by CD4+ Th1 cells that mainly secrete IFN-γ and TNF-α, important cytokines in the pathophysiology of the disease. Spontaneous remission is, in part, attributed ...
Decreased production of TNF-alpha by lymph node cells indicates experimental autoimmune encephalomyelitis remission in Lewis rats
(Instituto Oswaldo Cruz, Ministério da Saúde, 2010-05-01)
Experimental autoimmune encephalomyelitis (EAE) is mediated by CD4+ Th1 cells that mainly secrete IFN-γ and TNF-α, important cytokines in the pathophysiology of the disease. Spontaneous remission is, in part, attributed ...
Proteoglycans as potential biomarkers in odontogenic tumors
(2018)
Proteoglycans (PGs) are essential for normal cellular development; however, alterations of their concentrations
can promote tumor growth. To date, a limited number of studies report the presence of PGs in odontogenic
tumors ...
miR-210 and miR-152 as Biomarkers by Liquid Biopsy in Invasive Ductal Carcinoma
(Mdpi, 2021-01-01)
Detecting circulating microRNAs (miRNAs; miRs) by means of liquid biopsy is an important tool for the early diagnosis and prognosis of breast cancer (BC). We aimed to identify and validate miR-210 and miR-152 as non-invasive ...
In situ proteomic analysis of glioblastoma multiforme: a translational approach to improve prognostic/diagnostic routines
(2020-01-01)
In order to evaluate the use of matrix-assisted laser desorption ionization (MALDI) Mass Spectral Imaging (MSI) to Glioblastoma (GBM) studies, some sections of formalin fixed paraffin embedded samples of GBM tumors were ...
Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers
(MDPIImpacto de Componentes Alimentarios en la SaludGrupo Tándem Max Planck en NanobioingenieríaBasilea, Suiza, 2022)
Small stress proteins, biomarkers of cancer
(Nova Science Publishers, 2010)
Many oncogenic agents/events generate in cancer cells stress-responsive proteins, also known as heat shock proteins (HSPs). These proteins are implicated in the genesis as well as in the progression of cancer; the small ...
Moesin expression by tumor cells is an unfavorable prognostic biomarker for oral cancer
(BioMed Central, 2018)
Abstract
Background
Moesin is a member of the ERM (ezrin, radixin and moesin) proteins that participate in cell migration and tumor invasion through transductional signals ...
Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma
(2016-10-01)
Breast carcinoma (BC) corresponds to 23 % of all cancers in women, with 1.38 million new cases and 460,000 deaths worldwide annually. Despite the significant advances in the identification of molecular markers and different ...
DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance
(2020-01-01)
Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. On average, patients survive 14.6 months after diagnosis and less than 5% survive five ...