info:eu-repo/semantics/article
Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers
Registro en:
2072-666X
10.3390/mi11040411
Autor
Quinchia Cardona, Jennifer Paola
Echeverri, Danilo
Cruz Pacheco, Andrés Felipe
Maldonado Celis, María Elena
Orozco Holguín, Jahir
Institución
Resumen
ABSTRACT: The accurate determination of specific tumor markers associated with cancer with
non-invasive or minimally invasive procedures is the most promising approach to improve the
long-term survival of cancer patients and fight against the high incidence and mortality of this
disease. Quantification of biomarkers at different stages of the disease can lead to an appropriate and
instantaneous therapeutic action. In this context, the determination of biomarkers by electrochemical
biosensors is at the forefront of cancer diagnosis research because of their unique features such
as their versatility, fast response, accurate quantification, and amenability for multiplexing and
miniaturization. In this review, after briefly discussing the relevant aspects and current challenges
in the determination of colorectal tumor markers, it will critically summarize the development of
electrochemical biosensors to date to this aim, highlighting the enormous potential of these devices
to be incorporated into the clinical practice. Finally, it will focus on the remaining challenges and
opportunities to bring electrochemical biosensors to the point-of-care testing. COL0083811