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Identification of the cognate peptide-MHC target of T cell receptors using molecular modeling and force field scoring
(Pergamon-Elsevier Science Ltd, 2018-02)
Interactions of T cell receptors (TCR) to peptides in complex with MHC (p:MHC) are key features that mediate cellular immune responses. While MHC binding is required for a peptide to be presented to T cells, not all MHC ...
Identification of intracellular peptides in rat adipose tissue: Insights into insulin resistance
(WILEY-BLACKWELLHOBOKEN, 2012)
Intracellular peptides generated by the proteasome and oligopeptidases have been suggested to function in signal transduction and to improve insulin resistance in mice fed a high-caloric diet. The aim of this study was to ...
Collision-Induced Dissociation of Lys-Lys Intramolecular Crosslinked Peptides
(Elsevier Science IncNew YorkEUA, 2009)
ArrayPitope: Automated analysis of amino acid substitutions for peptide microarray-based antibody epitope mapping
(Public Library of Science, 2017-01)
Identification of epitopes targeted by antibodies (B cell epitopes) is of critical importance for the development of many diagnostic and therapeutic tools. For clinical usage, such epitopes must be extensively characterized ...
NetMHCstab – predicting stability of peptide–MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery
(Wiley, 2014-01)
Major histocompatibility complex class I (MHC-I) molecules play an essential role in the cellular immune response, presenting peptides to cytotoxic T lymphocytes (CTLs) allowing the immune system to scrutinize ongoing ...
Enhancing Mass Spectrometry-Based MHC-I Peptide Identification Through a Targeted Database Search Approach
(Humana Press, 2019-08)
MHC-bound peptide ligands dictate the activation and specificity of CD8+ T- cells-based and thus are important for devising T-cell immunotherapies. In recent times, advances in mass spectrometry (MS) have enabled the precise ...
Identification and quantification of somathropin modifications by peptide mapping with UPLC/HDMSE
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Computer aided identification of a Hevein-like antimicrobial peptide of bell pepper leaves for biotechnological use
(BioMed Central Genomics, 2017)