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Cellular proliferation rate, and IGFBP-2 and -3 and estradiol receptor alpha expression in the mammary gland of dairy heifers naturally infected with gastrointestinal nematodes during development
(Elsevier, 2014-08)
Mammary ductal morphogenesis during prepuberty occurs mainly in response to insulin-like growth factor-1 (IGF-1) and estradiol stimulation. Dairy heifers infected with gastrointestinal nematodes have reduced IGF-1 levels, ...
Glyphosate-based herbicide induces hyperplastic ducts in the mammary gland of aging Wistar rats
(Elsevier Ireland, 2019-11)
Adverse effects of glyphosate-based herbicide (GBH) exposure on endocrine-related tissues have been reported. Our aim was to determine whether early postnatal exposure to a GBH produces long-term effects on the mammary ...
Postnatal exposure to a glyphosate-based herbicide modifies mammary gland growth and development in Wistar male rats
(Pergamon-Elsevier Science Ltd, 2018-08)
Our aim was to evaluate whether postnatal exposure to a glyphosate-based herbicide (GBH) modifies mammary gland development in pre- and post-pubertal male rats. From postnatal day 1 (PND1) to PND7, male rats were injected ...
Perinatal Exposure to Bisphenol A or Diethylstilbestrol Increases the Susceptibility to Develop Mammary Gland Lesions After Estrogen Replacement Therapy in Middle-Aged Rats
(2017-04-01)
The development of the mammary gland is a hormone-regulated event. Several factors can dysregulate its growth and make the gland more susceptible to cellular transformation. Among these factors, perinatal exposure to ...
Squamous Cell Carcinoma of Mammary Gland in Domestic Cat
(UNIV FED RIO GRANDE DO SULPORTO ALEGRE RS, 2012)
Background: In the feline species, 80% to 93% of neoplasias in the mammary gland are malignant, being the majority carcinomas. Among them, there is the mammary squamous cell carcinoma, which amounts to a very rare neoplasm ...
The hyperplastic phenotype in PR-A and PR-B transgenic mice: lessons on the role of estrogen and progesterone receptors in the mouse mammary gland and breast cancer.
(Elsevier, 2013)
Progesterone receptor (PR) belongs to the superfamily of steroid receptors and mediates the action of progesterone in its target tissues. In the mammary gland, in particular, PR expression is restricted to the luminal ...
Impact of endocrine disruptor hexachlorobenzene on the mammary gland and breast cancer: The story thus far
(Academic Press Inc Elsevier Science, 2019-06)
Breast cancer incidence is increasing globally and exposure to endocrine disruptors has gained importance as a potential risk factor. Hexachlorobenzene (HCB) was once used as a fungicide and, despite being banned, considerable ...
Malignant adenomyo-epithelioma in a feline mammary gland
(Desconhecida, 2017)
Paternal selenium deficiency but not supplementation during preconception alters mammary gland development and 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in female rat offspring
(Wiley-Blackwell, 2016-10-15)
Breast cancer is a global public health problem and accumulating evidence indicates early-life exposures as relevant factors in the disease risk determination. Recent studies have shown that paternal nutrition can influence ...