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Regulamentação sanitária de medicamentos
(2011-06-28)
The health regulation of drugs is one of eight guidelines issued within the National Drug Policy. It refers to the supervision and regulation of drug registration and the approval of operations, from the manufacturers to ...
Therapeutic monitoring of antibiotics. New methodologies: biosensors
(SOC MEDICA SANTIAGO, 2015)
The pharmacokinetics of antibiotics, especially in severely ill patients, may be profoundly altered due to multiple pathophysiological changes. Recent studies have shown that empiric dosing recommendations for ICU patients ...
Applications of Nanosystems to Anticancer Drug Therapy (Part I. Nanogels, Nanospheres, Nanocapsules)
(Bentham Science Publishers, 2014)
One of the greatest challenges in cancer drug therapy is to maximize the effectiveness of the active agent while reducing its systemic adverse effects. To add more, many widely-used chemoterapeutic agents present unfavorable ...
Pharmacomagnetography to evaluate the performance of magnetic enteric-coated tablets in the human gastrointestinal tract
(2021-04-01)
A magnetic enteric-coated tablet containing diclofenac sodium was produced, and its performance under physiological and disturbed gastrointestinal motility was assessed through pharmacomagnetography analysis. In vitro ...
Monitoring the outcomes of interventions against Taenia solium: options and suggestions
(Wiley, 2015)
There is an increasing interest in reducing the incidence of human neurocysticercosis, caused by infection with the larval stage of Taenia solium. Several intervention trials are currently assessing various options for ...
Personalized Medicine for Antibiotics: The Role of Nanobiosensors in Therapeutic Drug Monitoring
(Journal of Personalized Medicine, 2020-09-25)
Due to the high bacterial resistance to antibiotics (AB), it has become necessary to adjust
the dose aimed at personalized medicine by means of therapeutic drug monitoring (TDM). TDM is a
fundamental tool for measuring the ...
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach
(Sociedade Brasileira de Dermatologia, 2020)
Adverse drug events in an intensive care unit of a university hospital
(SPRINGER, 2011)
Purpose Adverse drug events (ADEs) are harmful and occur with alarming frequency in critically ill patients. Complex pharmacotherapy with multiple medications increases the probability of a drug interaction (DI) and ADEs ...