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Analysis of telomere length in mantle cell lymphoma
(Wiley Blackwell Publishing, Inc, 2009-11)
Mantle cell lymphoma (MCL) is a well defined lymphoid neoplasm genetically characterized by the t(11;14)(q13;q32). Telomeres play an essential role in preserving chromosomal integrity and genomic stability; their shortening ...
Padronização da técnica de qPCR para quantificação do comprimento relativo telomérico no Caenorhabditis elegans
(Universidade Federal de Minas GeraisUFMG, 2016-07-22)
Telomeres have a fundamental role in cellular replication and through their length it is possible to estimate cellular life span mean. Evidence has shown that factors such as environmental, social, nutritional and ...
Body mass index is negatively associated with telomere length: A collaborative cross-sectional meta-analysis of 87 observational studies
(Oxford University Press, 2018)
© 2018 American Society for Nutrition. Background: Even before the onset of age-related diseases, obesity might be a contributing factor to the cumulative burden of oxidative stress and chronic inflammation throughout the ...
Telomere and Telomerase Biology
(Elsevier B.V., 2015)
Telomere and Telomerase Biology
(Elsevier B.V., 2015)
Absolute qPCR for Measuring Telomere Length in Bone Marrow Samples of Plasma Cell Disorders
(Humana Press, 2015-02)
Telomere length (TL) is currently used as an emerging biomarker in understanding the development/progression of hematological malignancies. The absolute quantitative PCR (qPCR) methodology has allowed the study of TL from ...
Expression profile of telomere-associated genes in multiple myeloma
(Wiley Blackwell Publishing, Inc, 2012-12)
To further contribute to the understanding of multiple myeloma, we have focused our research interests on the mechanisms by which tumour plasma cells have a higher survival rate than normal plasma cells. In this article, ...
Exposure to Inorganic Arsenic Is Associated with Increased Mitochondrial DNA Copy Number and Longer Telomere Length in Peripheral Blood
(Frontiers, 2016-08)
Background: Exposure to inorganic arsenic (iAs) through drinking water causes cancer. Alterations in mitochondrial DNA copy number (mtDNAcn) and telomere length in blood have been associated with cancer risk. We elucidated ...
The relationship of telomere length to baseline corticosterone levels in nestlings of an altricial passerine bird in natural populations.
(2016)
Background: Environmental stressors increase the secretion of glucocorticoids that in turn can shorten telomeres via oxidative damage. Modification of telomere length, as a result of adversity faced early in life, can ...