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Modulation and recruitment of inducible regulatory T cells by first trimester trophoblast cells
(Wiley Blackwell Publishing, Inc, 2012-01)
Problem The specialized regulatory T-cells (Treg) population, essential for maternal tolerance of the fetus, performs its suppressive actions in the critical peri-implantation phase of pregnancy. In the present work, we ...
Regulatory T cell phenotype and anti osteoclastogenic function in experimental periodontitis
(Nature, 2020)
The alveolar bone resorption is a distinctive feature of periodontitis progression and determinant for tooth loss. Regulatory T lymphocytes (Tregs) display immuno-suppressive mechanisms and tissue repairing functions, which ...
Mechanisms involved in the expansion of Tregs during pregnancy: Role of IL-2/STAT5 signalling
(Elsevier Ireland, 2011-03)
Several studies have reported that the fine-tuning of regulatory T cells (Tregs) is required for a successful pregnancy and for the control of autoimmune diseases. Here, we review the mechanisms that control the expansion ...
The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells
(Rockefeller University Press, 2020)
Host genetic background affects regulatory T-cell activity that influences the magnitude of cellular immune response against Mycobacterium tuberculosis
(NATURE PUBLISHING GROUP, 2011)
Using two mouse strains with different abilities to generate interferon (IFN)-gamma production after Mycobacterium tuberculosis infection, we tested the hypothesis that the frequency and activity of regulatory T (Treg) ...
Characterization of CD4(+)CD25(+) natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis
(FEDERATION AMER SOC EXP BIOL, 2008)
Periodontitis is an infectious disease, where putative periodontopathogens trigger chronic inflammatory and immune responses against periodontal structures, in which an unbalanced host response is also determinant to the ...
CD4+FOXP3+cells produce IL-10 in the spleens of dogs with visceral leishmaniasis
(Elsevier B.V., 2014-05-28)
Visceral Leishmaniasis (VL) is caused by intracellular parasites of the genus Leishmania that affect humans and several animal species. Dogs are one of the main urban reservoirs of the parasite and play a central role in ...
Trichostatin A Promotes the Generation and Suppressive Functions of Regulatory T Cells
(Hindawi, 2013)
Regulatory T cells are a specific subset of lymphocytes that suppress immune responses and play a crucial role in the maintenance
of self-tolerance. They can be generated in the thymus as well as in the periphery through ...
Trichostatin a promotes the generation and suppressive functions of regulatory T cells
(Hindawi Limited, 2013-05)
Regulatory T cells are a specific subset of lymphocytes that suppress immune responses and play a crucial role in the maintenance of self-tolerance. They can be generated in the thymus as well as in the periphery through ...
Trichostatin a promotes the generation and suppressive functions of regulatory T cells
(2013)
Regulatory T cells are a specific subset of lymphocytes that suppress immune responses and play a crucial role in the maintenance of self-tolerance. They can be generated in the thymus as well as in the periphery through ...