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Lactadherin: From a Well-Known Breast Tumor Marker to a Possible Player in Extracellular Vesicle-Mediated Cancer Progression
(2022)
Lactadherin is a secreted glycoprotein associated with the milk fat globule membrane, which is highly present in the blood and in the mammary tissue of lactating women. Several biological functions have been associated ...
Investment specific technological progress and structural change
(Faculdade de Economia, Administração e Contabilidade da Universidade de São Paulo (FEA-USP), 2010)
In this paper we introduce investment specific technical progress into Pasinetti's model of structural change. Our aim is to assess the effects of embodied technical progress on economic growth and macroeconomic variables. ...
A research agenda to guide progress on childhood obesity prevention in Latin America
(Wiley, 2017)
Childhood obesity rates in Latin America are among the highest in the world. This paper examines and evaluates the many efforts underway in the region to reduce and prevent further increases in obesity, identifies and ...
Yoghurt feeding inhibits promotion and progression of experimental colorectal cancer
(International Scientific Information, Inc., 2004-04)
Background: In BALB/c mice, a yogurt diet given before and after the carcinogen 1, 2 dymethylhydrazine (DMH) inhibited colon cancer. This paper studied at which stage of tumor development (initiation, promotion or progression) ...
DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression
(National Academy Of Sciences, 2016-07)
DNA damage tolerance facilitates the progression of replication forks that have encountered obstacles on the template strands. It involves either translesion DNA synthesis initiated by proliferating cell nuclear antigen ...
Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase
(Nature Publishing Group, 2017-06)
Upon different types of stress, the gene encoding the mitosis-promoting phosphatase Cdc25C is transcriptionally repressed by p53, contributing to p53’s enforcement of a G2 cell cycle arrest. In addition, Cdc25C protein ...
Interplay of fibroblasts with anaplastic tumor cells promotes follicular thyroid cancer progression
(Nature Publishing Group, 2019-05)
Thyroid cancer is the most common endocrine malignancy. Anaplastic thyroid cancer is one of the most aggressive thyroid tumors. It is known that activation of oncogenes and/or inactivation of tumor suppressor genes in tumor ...
Calcineurin Regulates Progressive Motility Activation of Rhinella (Bufo) arenarum Sperm Through Dephosphorylation of PKC Substrates
(Wiley, 2014-10)
Animals with external fertilization, as amphibians, store their sperm in a quiescent state in the testis. When spermatozoa are released into natural fertilization media, the hypotonic shock triggers activation of sperm ...