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Oroidin Inhibits the Activity of the Multidrug Resistance Target Pdr5p from Yeast Plasma Membranes
(AMER CHEMICAL SOC, 2011)
Oroidin was isolated from the marine sponge Agelas sventres and inhibited the activity and function of Pdr5p, an enzyme responsible for the multidrug resistance phenotype in Saccharomyces cerevisiae. This compound may help ...
The protein synthesis inhibitors mycalamides A and E have limited susceptibility toward the drug efflux network
(John Wiley & Sons Inc, 2012-03-20)
The mycalamides belong to a family of protein synthesis inhibitors noted for antifungal, antitumour, antiviral, immunosuppressive, and nematocidal activities. Here we report a systematic analysis of the role of drug ...
ASOCIACIÓN DE ALGUNOS POLIMORFISMOS DE CITOCINAS EN LA RETINOPATÍA DIABÉTICA PROLIFERATIVA EN MESTIZOS MEXICANOS
(2011-11-24)
Type 2 diabetes (T2D) is a significantly growing public health problem worldwide, and 12 to 14 million people have been reported to be affected in Mexico. Diabetic Retinopathy (DR) is the most important ocular complication ...
Prenatal detection of congenital anomalies and related factors in Argentina
(Springer, 2020-07)
Congenital anomalies (CAs) are a leading cause of neonatal death. Many CAs can be diagnosed prenatally. To estimate the prenatal detection rate (PDR) of CA in hospitals participating in the RENAC (National Network of ...
Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy: the 2010 GLADAOF Lecture
(Hindawi Publishing Corporation, 2011-01-01)
This paper demonstrates multiple benefits of intravitreal bevacizumab (IVB) on diabetic retinopathy (DR) including diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) at 24 months of followup. This ...
Manifestations related to alterations in coagulation in systemic lupus erythematosus of juvenile onset. Case report and literature review
Haematological alterations are common in patients with systemic lupus erythematosus (SLE). These haematological manifestations may be expressed related to the involvement of cells affected and coagulation changes. The ...