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Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions
(2017-02)
Lippia alba (Verbenaceae Family) is an aromatic shrub native to Latin America, with recognized medicinal properties and a well-known high phenotypical plasticity in response to environmental factors. In order to identify ...
c-FLIP is involved in erythropoietin-mediated protection of erythroid-differentiated cells from TNF-α-induced apoptosis
(Academic Press Ltd - Elsevier Science Ltd, 2010-06)
The TNF-α (tumour necrosis factor) affects a wide range of biological activities, such as cell proliferation and apoptosis. Cell life or death responses to this cytokine might depend on cell conditions. This study focused ...
Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines
(John Wiley & Sons Ltd, 2011-04)
Natural occurring compounds are considered an important source of antitumoral agents. In the present study, the cytotoxic potential of three pentacyclic triterpenes isolated from Chuquiraga erinacea (Asteraceae), against ...
Human leukaemic cell lines synthesize hyaluronan to avoid senescence and resist chemotherapy
(Oxford Univ Press Inc, 2013-11)
Hyaluronan (HA) is one of the major components of the extracellular matrix. Several solid tumors produce high levels of HA, which promotes survival and multidrug resistance (MDR). HA oligomers (oHAs) can block HA effects. ...
Avaliação dos mecanismos envolvidos nas ações antitumorais do extrato etanólico de Artemisia vulgaris
(Universidade Federal de São Paulo (UNIFESP), 2021)
Artemisia vulgaris (AV) is a species of the genus Artemisia with an ancient history. This herb is known for having a wide content of bioactive compounds that exert anti-hypertensive, hepatoprotective, antispasmodic, ...