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Histamine in cancer immunology and immunotherapy. Current status and new perspectives
(John Wiley & Sons Inc., 2021-10)
Cancer is the second leading cause of death globally and its incidence and mortality are rapidly increasing worldwide. The dynamic interaction of immune cells and tumor cells determines the clinical outcome of cancer. ...
Innate and adaptive immunity gene expression of human keratinocytes cultured of severe burn injury
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-01-01)
PURPOSE:Evaluate the expression profile of genes related to Innate and Adaptive Immune System (IAIS) of human Primary Epidermal keratinocytes (hPEKP) of patients with severe burns.METHODS: After obtaining viable fragments ...
Modulation of cell proliferation, survival and gene expression by RAGE and TLR signaling in cells of the innate and adaptive immune response: role of p38 MAPK and NF-KB
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2014)
Modulation of cell proliferation, survival and gene expression by RAGE and TLR signaling in cells of the innate and adaptive immune response: role of p38 MAPK and NF-KB
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2014)
Detection of viral infections by innate immunity
Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral innate immune
system as they detect conserved viral pathogen-associated molecular patterns (PAMPs). A successful host
response to ...
The role of neutrophils in hypertension
(MDPI AG, 2020-11-02)
It is well accepted that the immune system and some cells from adaptive and innate immunity are necessary for the initiation/perpetuation of arterial hypertension (AH). However, whether neutrophils are part of this group ...
Type I interferon response and innate immune sensing of cancer.
(Elsevier, 2013-02)
Unexpectedly, many cancers appear to induce a spontaneous adaptive T cell response. The presence of a T cell infiltrate has been linked to favorable clinical outcome in multiple cancer types. However, the innate immune ...
Physiology and Pathology of Innate Immune Response Against Pathogens
(IntechOpen, 2017-12-20)
Pathogen infections are recognized by the immune system, which consists of two types
of responses: an innate immune response and an antigen-specific adaptive immune
response. The innate response is characterized by being ...